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1.11.1.24: thioredoxin-dependent peroxiredoxin

This is an abbreviated version!
For detailed information about thioredoxin-dependent peroxiredoxin, go to the full flat file.

Word Map on EC 1.11.1.24

Reaction

2 R'-SH +

ROOH
=
R'-S-S-R'
 +
H2O
 +
ROH

Synonyms

1-Cys peroxiredoxin, 1-Cys Prx, 1-Cys type Prx, 2-Cys peroxiredoxin, 2-Cys peroxiredoxin 4, 2-Cys Prx, 2-Cys type Prx, 25 kDa thiol-specific oxidant, 2Cys-peroxiredoxin, AbTPx1, AbTPx2, Ac-1-Cys Prx, Ahp, Ahp1, AhpC, AhpC-like peroxiredoxin, AhpC-like Prx, AhpC2, AhpE, alkyl hydroperoxide reductase, alkyl hydroperoxide reductase C component, alkyl hydroperoxide reductase subunit C, alkylhydroperoxide reductase subunit C, APE2278, ApTPx, AsPrx, atypical two-cysteine peroxidase, bacterioferritin comigratory protein, BCP, Bcp1, Bcp3, Bcp4, BiPrx1, BiTPx1, BmTPx-Q, C-PrxII, C2C-Prx, calpromotin, CIC-Prx, cPrx I, cPrx II, CPX, DTT-dependent peroxidase, EC 1.11.1.15, EcTpx, EgTPx, FhePrx, GPX, HBP23/Prx I, heme-binding protein 23/peroxiredoxin, LimTXNPx, More, MPX, MtTPx, natural killer enhancing factor-B, ncgl2403, NES-Prx1, NLS-Prx1, nuclear export signal-Prx1, nuclear localization signal-Prx1, peroxiredoxin, peroxiredoxin 1, peroxiredoxin 2, peroxiredoxin 3, peroxiredoxin 4, peroxiredoxin 5, peroxiredoxin 6, peroxiredoxin I, peroxiredoxin II, peroxiredoxin III, peroxiredoxin IV, peroxiredoxin Q, peroxiredoxin V, peroxiredoxin-1, peroxiredoxin-3, peroxiredoxin-4, PfTrx-Px1, PfTrx-Px2, PH1217, PH1217 protein, PRDX I, PRDX II, PRDX III, PRDX-2, PRDX-3, PRDX2, PRDX5, Prdx6, Prx, Prx 2, Prx 3, Prx 4, Prx I, Prx II, Prx III, PRx IV, Prx Q, Prx Q1, Prx Q2, Prx V, Prx VI, Prx-4, Prx1, Prx2, Prx3, Prx5, PrxII, PrxII F, PrxQ, PrxT, PrxV, PrxVI, Rv2238c, SAOUHSC_01822, SF2523, sll0221, sll0755, sll1621, slr0242, slr1198, SSO2613, tgTPx1/2, TgTrx-Px1, TgTrx-Px2, thiol-specific antioxidant/protector protein, thioredoxin peroxidase, thioredoxin peroxidase 1, thioredoxin peroxidase 1/2, thioredoxin peroxidase 2, thioredoxin peroxidase B, thioredoxin peroxidase II, thioredoxin peroxidase TSA2, thioredoxin-dependent alkyl hydroperoxide reductase, thioredoxin-dependent peroxiredoxin Q, thioredoxin-dependent thiol peroxidase, TM0807, torin, TP0509, Tpx, TPx I, TPx II, TPx-1, TPx-B, TPx1, TPx1/2, TPX2, Tpx3, TRIREDRAFT_47136, tryparedoxin peroxidase, tryparedoxin/peroxynitrite oxidoreductase, Ts2-CysPrx, TSA, TSA thioredoxin peroxidase Tpx, Tsa1, TsaA, two-cysteine peroxiredoxin, TXNPx, type II peroxiredoxin, typical 2-Cys peroxiredoxin, typical 2-Cys Prx

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.24 thioredoxin-dependent peroxiredoxin

Expression

Expression on EC 1.11.1.24 - thioredoxin-dependent peroxiredoxin

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
72-fold upregulation is induced by a short oxygen exposure
enzyme expression is neither induced by H2O2 nor controlled by OxyR
exposure to various oxidative stressors, such as cold (8°C), heat (35°C), bacteria (Escherichia coli), and insecticides (chlorpyrifos and lambda-cyhalothrin), significantly upregulates transcription of CsTpx3
following the addition of 1 mM hydrogen peroxide to Synechocystis cultures, the transcript level of the gene decreases during the first 15 min and thereafter increases to the initial levels
following the addition of 1 mM hydrogen peroxide to Synechocystis cultures, the transcript level of the gene decreases during the first 15 min and thereafter increases to the initial levels. Induction of the 2-cys prx gene in response to high light intensity
following the addition of 1 mM hydrogen peroxide to Synechocystis cultures, the transcript level of the gene decreases during the first 15 min and thereafter increases to the initial levels. The transcript level of the prxII gene increases during nitrogen starvation
in Pyrococcus horikoshii cells the enzyme is induced by oxygen and hydrogen peroxide
induced as a cellular adaptation in response to the addition of exogenous H2O2
isoform Prx1 is occasionally expressed only in cells exposed to high levels of H2O2
isoform Prx2 is induced by trace amounts of H2O2 and thereby residential in cells grown aerobically
RNAi-induced BiPrx1 knockdown in worker bees causes upregulated expression of BiTPx1. Reciprocally, BiTPx1 RNAi knockdown causes upregulation of BiPrx1 expression in the fat body
SigH activates prxQ expression by directly binding to the prxQ promoter
stress-inducible enzyme
the expression level gradually elevates during exponential growth until mid-log phase growth beyond which the expression level is decreased
the expression level gradually elevates during exponential growth until mid-log phase growth. The enzyme (BCP) is induced 3fold by the oxidative stress given by changing the growth conditions from the anaerobic to aerobic culture
the mRNA expression is upregulated 24 h after treatment with emamectin benzoate
-
transcription of the gene increases by the addition of exogenous oxygen and by the addition of an oxidative stress-inducing reagent, and reaches maximum within 30 min
when incubated with chloroquine diphosphate salt for 24 h in vitro, the expression of BmTPx-Q shows a marked downward trend with the increase of drug concentration
-