1.11.2.2: myeloperoxidase

This is an abbreviated version!
For detailed information about myeloperoxidase, go to the full flat file.

Word Map on EC 1.11.2.2

1.11.2.2

neutrophil

necrosis

leukocyte

tnf

malondialdehyde

dismutase

colitis

reperfusion

pulmonary

artery

endothelial

polymorphonuclear

ischemia

catalase

monocyte

sham

bowel

lps

mucosal

ulcer

edema

bronchoalveolar

wistar

granulocyte

lavage

lipopolysaccharide

sod

hypochlorous

hocl

vasculitis

ischemia-reperfusion

factor-alpha

macroscopic

tnf-alpha

eosinophil

elastase

dextran

ancas

myeloid

dss-induced

degranulation

glomerulonephritis

lactoferrin

icam-1

granulomatosis

antineutrophil

instil

medicine

carrageenan-induced

lactoperoxidase

crescent

analysis

Reaction

Cl-

+

H2O2

+

H+

=

HClO

+

H2O

Synonyms

donor, hydrogen peroxide oxidoreductase, donor, hydrogen peroxideoxidoreductase, donor: H2O2 oxidoreductase, donor:H2O2 oxidoreductase, donor:hydrogen peroxide oxidoreductase, donor:hydrogen-peroxide oxidoreductase, EC 1.11.1.7, epx2a, hemi-MPO, hemi-myeloperoxidase, LPO, MPO, MPX, myeloperoxidase, peroxinectin, properoxinectin, recombinant human MPO, rhMPO, tissue myeloperoxidase

ECTree

1 Oxidoreductases

1.11 Acting on a peroxide as acceptor

1.11.2 Peroxygenases

1.11.2.2 myeloperoxidase

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Results	in table
15	Activating Compound
4	AA Sequence
3	Application
4	Cloned(Commentary)
54	Cofactor
3	Crystallization (Commentary)
18939	Disease/ Diagnostics
2	Expression
22	General Information
1	General Stability
147	IC50 Value
266	Inhibitors
9	Ki Value [mM]
35	KM Value [mM]
9	Localization
7	Metals/Ions
16	Molecular Weight [Da]
65	Natural Substrates/ Products (Substrates)
90	Organism
1	Pathway
122	PDB ID
11	pH Optimum
1	pH Range
1	pH Stability
12	Posttranslational Modification
18	Purification (Commentary)
1	Reaction
90	Reference
98	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
190	Substrates and Products (Substrate)
19	Subunits
92	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
2	Temperature Stability [°C]
33	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 1.11.2.2 - myeloperoxidase

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0.00105

(2Z)-1-(2-aminophenyl)-3-phenylprop-2-en-1-one

Homo sapiens

at 37°C, pH not specified in the publication

-

0.00097

(2Z)-1-(3-aminophenyl)-3-phenylprop-2-en-1-one

Homo sapiens

at 37°C, pH not specified in the publication

-

0.00056

(2Z)-1-(4-aminophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one

Homo sapiens

at 37°C, pH not specified in the publication

-

0.00063

(2Z)-1-(4-aminophenyl)-3-(4-nitrophenyl)prop-2-en-1-one

Homo sapiens

at 37°C, pH not specified in the publication

-

0.00054

(2Z)-1-(4-aminophenyl)-3-(furan-2-yl)prop-2-en-1-one

Homo sapiens

at 37°C, pH not specified in the publication

-

0.01

(2Z)-1-(4-aminophenyl)-3-(naphthalen-1-yl)prop-2-en-1-one, (2Z)-1-(4-aminophenyl)-3-(naphthalen-2-yl)prop-2-en-1-one

Homo sapiens

IC50 above 0.01 mM, at 37°C, pH not specified in the publication

-

0.01

(2Z)-1-(4-aminophenyl)-3-(naphthalen-2-yl)prop-2-en-1-one

Homo sapiens

-

IC50 above 0.01 mM, at 37°C, pH not specified in the publication

-

0.00053

(2Z)-1-(4-aminophenyl)-3-(thiophen-2-yl)prop-2-en-1-one

Homo sapiens

at 37°C, pH not specified in the publication

-

0.00056

(2Z)-1-(4-aminophenyl)-3-phenylprop-2-en-1-one

Homo sapiens

at 37°C, pH not specified in the publication

-

0.00063

(2Z)-1-(4-aminophenyl)-3-[4-(trifluoromethyl)phenyl]prop-2-en-1-one

Homo sapiens

at 37°C, pH not specified in the publication

-

0.00025

(5-(((5-amino-3H-[1,2,3]triazolo[4,5-b]pyridin-7-yl)oxy)methyl)-2-phenyl-2H-1,2,3-triazol-4-yl)methanol

Homo sapiens

at pH 7.4 and 25°C

-

0.01

1,4-bis[(2-fluorophenyl)methyl]piperazine

Homo sapiens

IC50 above 0.01 mM, at pH 7.4 and 25°C

0.01

1,4-bis[(3-fluorophenyl)methyl]piperazine

Homo sapiens

IC50 above 0.01 mM, at pH 7.4 and 25°C

0.01

1,4-bis[(4-fluorophenyl)methyl]piperazine

Homo sapiens

IC50 above 0.01 mM, at pH 7.4 and 25°C

0.01

1,4-dibenzylpiperazine

Homo sapiens

IC50 above 0.01 mM, at pH 7.4 and 25°C

0.0014

2,2'-[piperazine-1,4-diylbis(methylene)]diphenol

Homo sapiens

IC50 above 0.01 mM, at pH 7.4 and 25°C

0.00066

2-(2-[[(3-fluorophenyl)methyl]amino]ethyl)phenol

Homo sapiens

at pH 7.4 and 25°C

0.00116

2-(2-[[(4-fluorophenyl)methyl]amino]ethyl)phenol

Homo sapiens

at pH 7.4 and 25°C

0.00003

2-(3,5-bistrifluoromethylbenzylamino)-6-oxo-1H-pyrimidine-5-carbohydroxamic acid

Homo sapiens

at pH 7.4, temperature not specified in the publication

0.00027

2-(3-[[(2-fluorophenyl)methyl]amino]propyl)phenol

Homo sapiens

at pH 7.4 and 25°C

0.00035

2-(3-[[(2-hydroxyphenyl)methyl]amino]propyl)phenol

Homo sapiens

at pH 7.4 and 25°C

0.00037

2-(3-[[(3-fluorophenyl)methyl]amino]propyl)phenol

Homo sapiens

at pH 7.4 and 25°C

0.00049

2-(3-[[(4-fluorophenyl)methyl]amino]propyl)phenol

Homo sapiens

at pH 7.4 and 25°C

0.00067

2-([[2-(2-fluorophenyl)ethyl]amino]methyl)phenol

Homo sapiens

at pH 7.4 and 25°C

0.00065

2-([[2-(2-hydroxyphenyl)ethyl]amino]methyl)phenol

Homo sapiens

at pH 7.4 and 25°C

0.00185

2-([[2-(2-methoxyphenyl)ethyl]amino]methyl)phenol

Homo sapiens

at pH 7.4 and 25°C

0.000085

2-([[2-(5-fluoro-1H-indol-3-yl)ethyl]amino]methyl)phenol

Homo sapiens

at pH 7.4 and 25°C

0.00037

2-([[3-(2-fluorophenyl)propyl]amino]methyl)phenol

Homo sapiens

at pH 7.4 and 25°C

0.0025

2-([[3-(2-methoxyphenyl)propyl]amino]methyl)phenol

Homo sapiens

at pH 7.4 and 25°C

0.000054

2-([[3-(5-fluoro-1H-indol-3-yl)propyl]amino]methyl)phenol

Homo sapiens

at pH 7.4 and 25°C

0.0005

2-aminobenzoic acid hydrazide

Homo sapiens

at pH 5.6 and 25°C

0.01

2-[(piperidin-1-yl)methyl]phenol

Homo sapiens

IC50 above 0.01 mM, at pH 7.4 and 25°C

0.01

2-[(piperidin-3-yl)methyl]phenol

Homo sapiens

IC50 above 0.01 mM, at pH 7.4 and 25°C

0.0027

2-[2-(benzylamino)ethyl]phenol

Homo sapiens

at pH 7.4 and 25°C

0.00036

2-[3-(benzylamino)propyl]phenol

Homo sapiens

at pH 7.4 and 25°C

0.0007

2-[[(2-phenylethyl)amino]methyl]phenol

Homo sapiens

at pH 7.4 and 25°C

0.0012

2-[[(3-phenylpropyl)amino]methyl]phenol

Homo sapiens

at pH 7.4 and 25°C

0.000026

3-((5-amino-3H-[1,2,3]triazolo[4,5-b] pyridin-7-yl)methyl)benzonitrile

Homo sapiens

at pH 7.4 and 25°C

-

0.00127

3-(dimethylamino) benzoic acid hydrazide

Homo sapiens

at pH 5.6 and 25°C

0.0006

3-isobutyl-2-thioxo-7H-purin-6-one

Homo sapiens

at pH 7.4, temperature not specified in the publication

-

0.00025

4'-amino-4-fluorochalcone

Homo sapiens

-

pH not specified in the publication, temperature not specified in the publication

0.00025

4'-amino-4-methylchalcone

Homo sapiens

-

pH not specified in the publication, temperature not specified in the publication

0.000265

4'-aminochalcone

Homo sapiens

-

pH not specified in the publication, temperature not specified in the publication

0.000018

4-(5-fluoro-1H-indol-3-yl)butanamide

show

0.000024 - 0.000026

4-(7-fluoro-1H-indol-3-yl)butanamide

show

0.1427

4-(trifluoromethyl) benzoic acid hydrazide

Homo sapiens

at pH 5.6 and 25°C

0.00071

4-amino benzoic acid hydrazide

Homo sapiens

at pH 5.6 and 25°C

0.0003 - 0.004

4-aminobenzoic acid hydrazide

show

0.02245

4-fluorobenzoic acid hydrazide

Homo sapiens

at pH 5.6 and 25°C

0.05462

4-nitrobenzoic acid hydrazide

Homo sapiens

at pH 5.6 and 25°C

0.00052

4-[(1Z)-3-(4-aminophenyl)-3-oxoprop-1-en-1-yl]benzonitrile

Homo sapiens

at 37°C, pH not specified in the publication

-

0.000034 - 0.000044

5-(7-fluoro-1H-indol-3-yl)pentanamide

show

0.00073

5-chlorotryptamine

Homo sapiens

-

IC50: 0.00073 mM

0.00079 - 0.0101

5-fluorotryptamine

show

0.0000085

7-(((5-(difluoromethyl)-2-phenyl-2H-1,2,3-triazol-4-yl)methyl)thio)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.0004

7-((1-phenyl-1H-1,2,3-triazol-4-yl)methoxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.00016

7-((2'-fluorobiphenyl-3-yl)methoxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.0000067

7-((2,6-dichlorobenzyl)oxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.0000046

7-((2,6-dichlorobenzyl)thio)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000026

7-((2-(1H-pyrazol-1-yl)benzyl)oxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.00072

7-((2-(methylsulfonyl)benzyl)oxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.0000087

7-((2-fluorobenzyl)thio)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000023

7-((3'-fluoro-2-methylbiphenyl-3-yl)methoxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000021

7-((3'-fluorobiphenyl-3-yl)methoxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.00012

7-((3-phenylisoxazol-5-yl)methoxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000024

7-((4-chloro-3'-fluorobiphenyl-3-yl)methoxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000012

7-((5-(difluoromethyl)-2-phenyl-2H-1,2,3-triazol-4-yl)methoxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000027

7-((5-methyl-2-phenyl-2H-1,2,3-triazol-4-yl)methoxy)-3H-[1,2,3]triazolo [4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.00029

7-((5-phenyloxazol-2-yl)methoxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.00099

7-(2-chlorobenzyl)-3H-[1,2,3]triazolo [4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000026

7-(2-chlorobenzyloxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000046

7-(2-fluorobenzyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.00003

7-(2-fluorobenzyloxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000026

7-(2-methyl-3-(1-methyl-1H-pyrazol-3-yl)benzyloxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000021

7-(3-(1-methyl-1H-pyrazol-3-yl)benzyloxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000078

7-(3-(1-methyl-1H-pyrazol-4-yl)benzyloxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.001426

7-(3-(trifluoromethyl)benzyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000032

7-(3-chlorobenzyl)-3H-[1,2,3]triazolo [4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000021

7-(3-chlorobenzyloxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000017

7-(3-methoxycarbonylbenzyl)-3H-[1,2,3]triazolo [4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000077

7-(3-phenylbenzyl)-3H-[1,2,3]triazolo [4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.0093

7-(4-chlorobenzyl)-3H-[1,2,3]triazolo [4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000026

7-(4-chlorobenzyloxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000029

7-(5-amino-3H-[1,2,3]triazolo[4,5-b]pyridin-7-yl)-13-(2-phenylethyl)-3,4,10,13-tetraazatricyclo[13.3.1.13,6]icosa-1(19),4,6(20),15,17-pentaen-12-one

Homo sapiens

-

pH and temperature not specified in the publication

-

0.00011

7-(benzyloxy)-3a,7a-dihydro-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000036

7-(benzyloxy)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.00019

7-(benzyloxy)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000188

7-(naphthalen-2-ylmethyl)-3H-[1,2,3] triazolo[4,5-b]pyridin-5-amine

Homo sapiens

at pH 7.4 and 25°C

-

0.000039

7-([1-[(3-benzylphenyl)methyl]-1H-pyrazol-3-yl]methyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000044

7-([1-[(3-phenoxyphenyl)methyl]-1H-pyrazol-3-yl]methyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000046

7-([1-[(3-[[(3S)-pyrrolidin-3-yl]oxy]phenyl)methyl]-1H-pyrazol-3-yl]methyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000043 - 0.00008

7-benzyl-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

show

-

0.00012

7-[(1-benzyl-1H-pyrazol-3-yl)methyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000055

7-[(1-phenyl-1H-pyrazol-3-yl)methyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.0001

7-[(1-[[3-(piperidin-4-yl)phenyl]methyl]-1H-pyrazol-3-yl)methyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000007

7-[(17S)-18-phenyl-16-oxa-2,8,9-triazapentacyclo[16.2.2.11,17.16,9.111,15]pentacosa-6(25),7,11(24),12,14-pentaen-5-yl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000001

7-[(1R)-1-phenyl-3-[(4-phenylbicyclo[2.2.2]octan-1-yl)amino]propyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000058

7-[(1R)-3-[[(1R)-2,3-dihydro-1H-inden-1-yl]amino]-1-phenylpropyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.00004

7-[(2-fluorobenzyl)sulfanyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000005

7-[(3R,4S,6S)-4-benzyl-2-oxa-7,13,14-triazatetracyclo[14.3.1.13,6.111,14]docosa-1(20),11(21),12,16,18-pentaen-10-yl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000026

7-[14'-oxa-3',4',10'-triazaspiro[cyclopentane-1,12'-tricyclo[13.3.1.13,6]icosane]-1'(19'),4',6'(20'),15',17'-pentaen-7'-yl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000036

7-[17-oxa-3,4,10-triazatetracyclo[16.3.1.13,6.112,16]tetracosa-1(22),4,6(24),12(23),13,15,18,20-octaen-7-yl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000008

7-[17-oxa-3,4,10-triazatetracyclo[17.3.1.13,6.112,16]pentacosa-1(23),4,6(25),12(24),13,15,19,21-octaen-7-yl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000025

7-[18-oxa-3,4,10-triazatetracyclo[17.3.1.13,6.112,16]pentacosa-1(23),4,6(25),12(24),13,15,19,21-octaen-7-yl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000014

7-[18-oxa-3,4,10-triazatetracyclo[17.3.1.13,6.113,17]pentacosa-1(23),4,6(25),13(24),14,16,19,21-octaen-7-yl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000017

7-[18-oxa-3,4,10-triazatetracyclo[18.3.1.13,6.113,17]hexacosa-1(24),4,6(26),13(25),14,16,20,22-octaen-7-yl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000031

7-[3-oxa-10,11,17-triazatetracyclo[16.2.2.14,8.110,13]tetracosa-4(24),5,7,11,13(23)-pentaen-14-yl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000021

7-[8,9,15-triazatetracyclo[16.3.1.12,6.18,11]tetracosa-1(22),2(24),3,5,9,11(23),18,20-octaen-12-yl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000058

7-[[1-(1,2,3,4-tetrahydroisoquinolin-6-ylmethyl)-1H-pyrazol-3-yl]methyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000053

7-[[1-(4-fluorophenyl)-1H-pyrazol-3-yl]methyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000085

7-[[1-(biphenyl-3-yl)-1H-pyrazol-3-yl]methyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000055

7-[[1-(biphenyl-3-ylmethyl)-1H-pyrazol-3-yl]methyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.00014

7-[[1-(isoquinolin-6-ylmethyl)-1H-pyrazol-3-yl]methyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000052

7-[[1-(naphthalen-2-ylmethyl)-1H-pyrazol-3-yl]methyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000054

7-[[1-(pyridin-2-yl)-1H-pyrazol-3-yl]methyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.000026

7-[[1-([3-[(2,3-dihydro-1H-isoindol-4-yl)oxy]phenyl]methyl)-1H-pyrazol-3-yl]methyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine

Homo sapiens

-

pH and temperature not specified in the publication

-

0.04083

benzoic acid hydrazide

Homo sapiens

at pH 5.6 and 25°C

0.0005

bis-2,2'-[(dihydro-1,3(2H,4H) pyrimidinediyl)bis(-methylene)]phenol

Homo sapiens

at pH 7.4 and 25°C

0.000001

catalase

Homo sapiens

at pH 6.0 and 25°C

-

0.00035

ceruloplasmin

Homo sapiens

at pH 6.0 and 25°C

-

0.027

cysteine

Homo sapiens

at pH 6.0 and 25°C

0.007

dapsone

Homo sapiens

at pH 6.0 and 25°C

0.00387

fisetin

Homo sapiens

-

0.032 - 0.05

HClO

show

0.2771

isoniazid

Homo sapiens

at pH 5.6 and 25°C

0.00208

kaempferol

Homo sapiens

-

0.00422

luteolin

Homo sapiens

-

0.043

methionine

Homo sapiens

at pH 6.0 and 25°C

0.0007

N-[(2-fluorophenyl)methyl]-3-(2-methoxyphenyl)propan-1-amine

Homo sapiens

at pH 7.4 and 25°C

0.00657 - 0.055

NaN3

show

0.025

NaSCN

Homo sapiens

at pH 6.0 and 25°C

0.0013

nitrite

Homo sapiens

-

at 21°C in 50 mM sodium phosphate buffer, pH 7.4

0.00127

quercetin

Homo sapiens

-

0.00058

RPYLKVNPR

Homo sapiens

at pH 6.0 and 25°C

0.021 - 0.032

Salicylhydroxamic acid

show

0.00663

taxifolin

Homo sapiens

-

0.0093

Urate

Homo sapiens

-

pH and temperature not specified in the publication

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Release 2023.1 (January 2023)