1.11.2.6: L-tyrosine peroxygenase
This is an abbreviated version!
For detailed information about L-tyrosine peroxygenase, go to the full flat file.
Word Map on EC 1.11.2.6
Reaction
Synonyms
L-tyrosine 3-hydroxylase, LmbB2, Orf13, TyrH
ECTree
1.11.2.6 L-tyrosine peroxygenaseAdvanced search results
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Substrates Products on EC 1.11.2.6 - L-tyrosine peroxygenase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
3-(4-hydroxylphenyl)propanoic acid + H2O2
3-(3,4-hydroxyphenyl)propanoic acid + H2O
-
-
-
-
?
3-chloro-L-tyrosine + H2O2
3-chloro-5-hydroxyl-L-tyrosine + L-dopa + Cl-
-
the enzyme performs oxidative C-H bond cleavage at C5 to generate 3-chloro-5-hydroxyl-L-tyrosine and oxygenation at C3 concomitant with a carbon-fluorine bond cleavage to yield L-dopa and chloride
-
-
?
3-fluoro-L-tyrosine + H2O2
3-fluoro-5-hydroxyl-L-tyrosine + L-dopa + F-
-
the enzyme performs oxidative C-H bond cleavage at C5 to generate 3-fluoro-5-hydroxyl-L-tyrosine and oxygenation at C3 concomitant with a carbon-fluorine bond cleavage to yield L-dopa and fluoride
-
-
?
3-iodo-L-tyrosine + H2O2
3-iodo-5-hydroxyl-L-tyrosine + L-dopa + I-
-
the enzyme performs oxidative C-H bond cleavage at C5 to generate 3-iodo-5-hydroxyl-L-tyrosine and oxygenation at C3 concomitant with a carbon-fluorine bond cleavage to yield L-dopa and iodide
-
-
?
3-nitro-L-tyrosine + H2O2
3-nitro-5-hydroxyl-L-tyrosine + H2O
-
-
-
-
?
additional information
?
-
-
no activity with L-phenylalanine and O-methyl-L-tyrosine
-
-
-
