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1.13.11.11: tryptophan 2,3-dioxygenase

This is an abbreviated version, for detailed information about tryptophan 2,3-dioxygenase, go to the full flat file.

Reaction

L-tryptophan
+
O2
=
N-formyl-L-kynurenine

Synonyms

33737, BRAFLDRAFT_210874, C28H8.11, hTDO, IDO-1, IDO-2, TDO, TDO2, TDOa, v1g157887, vCG5163, XcTDO

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.11 tryptophan 2,3-dioxygenase

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Results
in table
2
Activating Compound
4630
AA Sequence
2
Application
13
Cloned(Commentary)
10
Cofactor
2
Crystallization (Commentary)
184
Disease/ Diagnostics
12
Engineering
29
General Information
20
IC50 Value
26
Inhibitors
25
KM Value [mM]
1
Localization
4
Metals/Ions
21
Natural Substrates/ Products (Substrates)
20
Organism
8
Pathway
64
PDB ID
9
pH Optimum
3
Purification (Commentary)
3
Reaction
25
Reference by Title
34
Source Tissue
39
Substrates and Products (Substrate)
6
Subunits
28
Synonyms
1
Systematic Name
13
Temperature Optimum [°C]
7
Turnover Number [1/s]
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