1.13.11.11: tryptophan 2,3-dioxygenase

This is an abbreviated version, for detailed information about tryptophan 2,3-dioxygenase, go to the full flat file.

Reaction

Synonyms

33737, BRAFLDRAFT_210874, C28H8.11, hTDO, IDO-1, IDO-2, TDO, TDO2, TDOa, v1g157887, vCG5163, XcTDO

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.11 With incorporation of two atoms of oxygen

                1.13.11.11 tryptophan 2,3-dioxygenase

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Results

in table

2

Activating Compound

4525

AA Sequence

2

Application

13

Cloned(Commentary)

10

Cofactor

2

Crystallization (Commentary)

180

Disease/ Diagnostics

12

Engineering

29

General Information

20

IC50 Value

26

Inhibitors

25

KM Value [mM]

1

Localization

4

Metals/Ions

21

Natural Substrates/ Products (Substrates)

20

Organism

8

Pathway

60

PDB ID

9

pH Optimum

3

Purification (Commentary)

3

Reaction

25

Reference by Title

34

Source Tissue

39

Substrates and Products (Substrate)

6

Subunits

28

Synonyms

1

Systematic Name

13

Temperature Optimum [°C]

7

Turnover Number [1/s]