1.13.11.11: tryptophan 2,3-dioxygenase

This is an abbreviated version!
For detailed information about tryptophan 2,3-dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.11

1.13.11.11

indoleamine

kynurenine

immunotherapy

heme

serotonin

checkpoint

l-trp

n-formylkynurenine

quinolinic

tolerogenic

3-monooxygenase

3,4-dioxygenase

heme-containing

2,3-dioxygenase-1

tryptophan-degrading

3-hydroxyanthranilate

indoleamine-2,3-dioxygenase

picolinic

tryptophan-catabolizing

pyrrolase

3-hydroxykynurenine

medicine

drug development

Reaction

L-tryptophan

+

O2

=

N-formyl-L-kynurenine

Synonyms

33737, BRAFLDRAFT_210874, C28H8.11, EC 1.11.1.4, hTDO, IDO-1, IDO-2, IDO1, IDO2, indoleamine 2,3-dioxygenase 1, indoleamine 2,3-dioxygenase 2, TDO, TDO2, TDOa, tryptophan 2,3-dioxygenase, tryptophan 2,3-dioxygenase 2, tryptophan 2,3-dioxygenase-2, tryptophan-2,3-dioxygenase, v1g157887, vCG5163, XcTDO

ECTree

1 Oxidoreductases

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.13.11 With incorporation of two atoms of oxygen

1.13.11.11 tryptophan 2,3-dioxygenase

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Results	in table
2	Activating Compound
9810	AA Sequence
2	Application
14	Cloned(Commentary)
18	Cofactor
4	Crystallization (Commentary)
1191	Disease/ Diagnostics
4	Expression
54	General Information
4	General Stability
135	IC50 Value
146	Inhibitors
26	KM Value [mM]
1	Localization
4	Metals/Ions
3	Molecular Weight [Da]
39	Natural Substrates/ Products (Substrates)
55	Organism
9	Pathway
85	PDB ID
9	pH Optimum
3	Posttranslational Modification
24	Protein Variants
5	Purification (Commentary)
3	Reaction
45	Reference
63	Source Tissue
60	Substrates and Products (Substrate)
9	Subunits
64	Synonyms
1	Systematic Name
13	Temperature Optimum [°C]
8	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 1.13.11.11 - tryptophan 2,3-dioxygenase

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0.0004

(1R,2S)-2-([[6-(trifluoromethyl)-1H-indazol-4-yl]amino]methyl)cyclohexan-1-ol

Homo sapiens

22°C, pH 6.5

-

0.01124

(1R,2S)-2-[[(5-bromo-1H-indazol-4-yl)amino]methyl]cyclohexan-1-ol

Homo sapiens

22°C, pH 6.5

-

0.03916

(1R,2S)-2-[[(5-bromo-1H-indazol-7-yl)amino]methyl]cyclohexan-1-ol

Homo sapiens

22°C, pH 6.5

-

0.08419

(1R,2S)-2-[[(5-chloro-1H-indazol-7-yl)amino]methyl]cyclohexan-1-ol

Homo sapiens

22°C, pH 6.5

-

0.03324

(1R,2S)-2-[[(6-bromo-1-methyl-1H-indazol-4-yl)amino]methyl]cyclohexan-1-ol

Homo sapiens

22°C, pH 6.5

-

0.00004

(1R,2S)-2-[[(6-bromo-1H-indazol-4-yl)amino]methyl]cyclohexan-1-ol

Homo sapiens

shows efficacy against the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse motor coordination deficits, comparable to Madopar, an anti-Parkinson's disease medicine, 22°C, pH 6.5

-

0.00019

(1R,2S)-2-[[(6-bromo-1H-indazol-4-yl)amino]methyl]cyclohexyl acetate

Homo sapiens

22°C, pH 6.5

-

0.00013

(1R,2S)-2-[[(6-chloro-1H-indazol-4-yl)amino]methyl]cyclohexan-1-ol

Homo sapiens

22°C, pH 6.5

-

0.00041

(1R,2S)-2-[[(6-methyl-1H-indazol-4-yl)amino]methyl]cyclohexan-1-ol

Homo sapiens

22°C, pH 6.5

-

0.00009

(1S,2R)-2-[[(6-bromo-1H-indazol-4-yl)amino]methyl]cyclohexan-1-ol

Homo sapiens

22°C, pH 6.5

-

0.00003

(2E)-3-(8-fluoro-6,12-dioxo-6,12-dihydroindolo[2,1-b]quinazolin-2-yl)prop-2-enoic acid

Homo sapiens

pH and temperature not specified in the publication

-

0.0044

(4-phenyl-1,2-oxazol-5-yl)methanol

Homo sapiens

pH and temperature not specified in the publication

-

0.00121

(8-fluoro-6,12-dioxo-6,12-dihydroindolo[2,1-b]quinazolin-2-yl)boronic acid

Homo sapiens

pH and temperature not specified in the publication

-

0.000561

1-(2-methylbenzyl)-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.000768

1-(3-bromobenzyl)-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.000711

1-(3-chlorobenzyl)-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.000059

1-(3-[(4-acetyl-1-piperazinyl)carbonyl]benzyl)-1H-naphtho-[2,3-d][1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.00003

1-(3-[(4-methyl-1-piperazinyl)carbonyl]benzyl)-1H-naphtho-[2,3-d][1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.001586

1-(4-bromobenzyl)-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.00738

1-(4-fluorobenzyl)-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.001088

1-(4-methylbenzyl)-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.000176

1-(4-[(4-acetylpiperazin-1-yl)carbonyl]benzyl)-1H-naphtho-[2,3-d][1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.000209

1-(4-[(4-methoxypiperidin-1-yl)carbonyl]benzyl)-1Hnaphtho[2,3-d][1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.0135

1-(cyclopropylmethyl)-5-(1H-indol-3-yl)-1H-benzotriazole

Homo sapiens

37°C, pH 6.25

-

0.0039

1-(cyclopropylmethyl)-6-(1H-indol-3-yl)-1H-benzotriazole

Homo sapiens

37°C, pH 6.26

-

0.00015

1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethan-1-ol

Homo sapiens

22°C, pH 6.5

0.001745

1-[(3-methylphenyl)methyl]-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.00646

1-[(4-chlorophenyl)methyl]-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.00042

1-[(8-fluoro-6,12-dioxo-6,12-dihydroindolo[2,1-b]quinazolin-2-yl)methyl]piperidine-3-carboxylic acid

Homo sapiens

pH and temperature not specified in the publication

-

0.00045

1-[(8-fluoro-6,12-dioxo-6,12-dihydroindolo[2,1-b]quinazolin-2-yl)methyl]piperidine-4-carboxylic acid

Homo sapiens

pH and temperature not specified in the publication

-

0.00018

1-[(8-fluoro-6,12-dioxo-6,12-dihydroindolo[2,1-b]quinazolin-2-yl)methyl]proline

Homo sapiens

pH and temperature not specified in the publication

-

0.000048

1-[3-(4-morpholinylcarbonyl)benzyl]-1H-naphtho[2,3-d]-[1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.000116

1-[4-(morpholin-4-ylcarbonyl)benzyl]-1H-naphtho[2,3-d]-[1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.000108

1-[4-[(4-methylpiperazin-1-yl)carbonyl]benzyl]-1H-naphtho-[2,3-d][1,2,3]triazole-4,9-dione

Homo sapiens

pH 8.0, 37°C

0.000145

2-(4-[(4,9-dioxo-4,9-dihydro-1H-naphtho[2,3-d][1,2,3]-triazol-1-yl)methyl]phenyl)-N,N-diethylacetamide

Homo sapiens

pH 8.0, 37°C

0.00338

2-[(6-bromo-1H-indazol-4-yl)amino]-1-(3-chlorophenyl)ethan-1-ol

Homo sapiens

22°C, pH 6.5

-

0.1477

2-[(6-bromo-1H-indazol-4-yl)amino]-1-(4-hydroxyphenyl)ethan-1-one

Homo sapiens

22°C, pH 6.5

-

0.00204

2-[(6-bromo-1H-indazol-4-yl)amino]-2-(3-chlorophenyl)ethan-1-ol

Homo sapiens

22°C, pH 6.5

-

0.00033

2-[(6-bromo-1H-indazol-4-yl)amino]-2-phenylethan-1-ol

Homo sapiens

22°C, pH 6.5

-

0.0369

2-[5-(1H-indol-3-yl)-1H-benzotriazol-1-yl]-N,N-dimethylethan-1-amine

Homo sapiens

37°C, pH 6.31

-

0.00162

2-[5-(1H-indol-3-yl)-1H-benzotriazol-1-yl]acetamide

Homo sapiens

37°C, pH 6.27

-

0.0246

2-[6-(1H-indol-3-yl)-1H-benzotriazol-1-yl]-N,N-dimethylethan-1-amine

Homo sapiens

37°C, pH 6.32

-

0.00068

2-[6-(1H-indol-3-yl)-1H-benzotriazol-1-yl]acetamide

Homo sapiens

37°C, pH 6.28

-

0.00012

2-[[(6-bromo-1H-indazol-4-yl)amino]methyl]cyclohexan-1-ol

Homo sapiens

22°C, pH 6.5

-

0.025

3-methyl-4-phenyl-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.00009

3-[(4,9-dioxo-4,9-dihydro-1H-naphtho[2,3-d][1,2,3]triazol-1-yl)methyl]-N,N-diethylbenzamide

Homo sapiens

pH 8.0, 37°C

0.000167

3-[(4,9-dioxo-4,9-dihydro-1H-naphtho[2,3-d][1,2,3]triazol-1-yl)methyl]benzoic acid

Homo sapiens

pH 8.0, 37°C

0.017

3-[5-(1H-indol-3-yl)-1H-benzotriazol-1-yl]propane-1,2-diol

Homo sapiens

37°C, pH 6.46

-

0.0252

3-[6-(1H-indol-3-yl)-1H-benzotriazol-1-yl]propane-1,2-diol

Homo sapiens

37°C, pH 6.47

-

0.00029

4-(1H-pyrazol-1-yl)-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.0005

4-(3-chlorophenyl)-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.00033

4-(3-chlorophenyl)-imidazole

Homo sapiens

pH and temperature not specified in the publication

-

0.0031

4-(3-methoxyphenyl)-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.0016

4-(3-methyl-1H-pyrazol-1-yl)-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.00083

4-(4-chlorophenyl)-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.00034

4-(4-fluoro-1H-pyrazol-1-yl)-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.00058

4-(4-fluorophenyl)-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.0016

4-(4-methyl-1H-pyrazol-1-yl)-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.0017

4-(pyridin-2-yl)-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.0023

4-(pyridin-3-yl)-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.000029

4-(thiophen-2-yl)-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.000028

4-(thiophen-3-yl)-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.02702

4-([[(1S,2R)-2-hydroxycyclohexyl]methyl]amino)-1H-indazole-6-carboxylic acid

Homo sapiens

22°C, pH 6.5

-

0.00011

4-chlorophenyl-1,2,3-triazol-4-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.0078

4-cyclohexyl-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.00064

4-cyclopentyl-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.00014

4-phenyl-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.018

4-phenyl-1,2-thiazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.00048

4-phenylimidazole

Homo sapiens

pH and temperature not specified in the publication

0.01286

4-[(1Z)-2-[(6-bromo-1H-indazol-4-yl)amino]-N-hydroxyethanimidoyl]phenol

Homo sapiens

22°C, pH 6.5

-

0.000181

4-[(4,9-dioxo-4,9-dihydro-1H-naphtho[2,3-d][1,2,3]triazol-1-yl)methyl]-N,N-diethylbenzamide

Homo sapiens

pH 8.0, 37°C

0.000312

4-[(4,9-dioxo-4,9-dihydro-1H-naphtho[2,3-d][1,2,3]triazol-1-yl)methyl]benzoic acid

Homo sapiens

pH 8.0, 37°C

0.00185

4-[[(6-bromo-1H-indazol-4-yl)amino]methyl]phenol

Homo sapiens

22°C, pH 6.5

-

0.015

5-(1H-indol-3-yl)-1-(2,2,2-trifluoroethyl)-1H-benzotriazole

Homo sapiens

37°C, pH 6.23

-

0.00501

5-(1H-indol-3-yl)-1-methyl-1H-benzotriazol-4-amine

Homo sapiens

37°C, pH 6.17

-

0.00387

5-(1H-indol-3-yl)-1-methyl-1H-benzotriazole

Homo sapiens

37°C, pH 6.13

-

0.0369

5-(1H-indol-3-yl)-1-[(oxolan-2-yl)methyl]-1H-benzotriazole

Homo sapiens

37°C, pH 6.35

-

0.0441

5-(1H-indol-3-yl)-1-[(oxolan-3-yl)methyl]-1H-benzotriazole

Homo sapiens

37°C, pH 6.33

-

0.01773

5-(1H-indol-3-yl)-1-[(piperidin-4-yl)methyl]-1H-benzotriazole

Homo sapiens

37°C, pH 6.39

-

0.1186

5-(1H-indol-3-yl)-1-[2-(morpholin-4-yl)ethyl]-1H-benzotriazole

Homo sapiens

37°C, pH 6.37

-

0.0249

5-(1H-indol-3-yl)-1-[2-(piperazin-1-yl)ethyl]-1H-benzotriazole

Homo sapiens

37°C, pH 6.43

-

0.0261

5-(1H-indol-3-yl)-1-[2-(pyrrolidin-3-yl)ethyl]-1H-benzotriazole

Homo sapiens

37°C, pH 6.41

-

0.00385

5-(1H-indol-3-yl)-2-methyl-2H-benzotriazol-4-amine

Homo sapiens

37°C, pH 6.16

-

0.004

5-(1H-indol-3-yl)-2-methyl-2H-benzotriazole

Homo sapiens

37°C, pH 6.12

-

0.0011

5-(6-fluoro-1H-indol-3-yl)-1-methyl-1H-benzotriazole

Homo sapiens

37°C, pH 6.14

-

0.045

5-(6-fluoro-1H-indol-3-yl)-1-[2-(piperazin-1-yl)ethyl]-1H-benzotriazole

Homo sapiens

37°C, pH 6.44

-

0.0019

6-(1H-indol-3-yl)-1-(2,2,2-trifluoroethyl)-1H-benzotriazole

Homo sapiens

37°C, pH 6.24

-

0.00393

6-(1H-indol-3-yl)-1-methyl-1H-benzotriazol-7-amine

Homo sapiens

37°C, pH 6.18

-

0.00908

6-(1H-indol-3-yl)-1-methyl-1H-[1,2,3]triazolo[4,5-b]pyridine

Homo sapiens

37°C, pH 6.21

-

0.00132

6-(1H-indol-3-yl)-1-methyl-7-nitro-1H-benzotriazole

Homo sapiens

37°C, pH 6.22

-

0.0211

6-(1H-indol-3-yl)-1-[(oxolan-2-yl)methyl]-1H-benzotriazole

Homo sapiens

37°C, pH 6.36

-

0.0219

6-(1H-indol-3-yl)-1-[(oxolan-3-yl)methyl]-1H-benzotriazole

Homo sapiens

37°C, pH 6.34

-

0.02551

6-(1H-indol-3-yl)-1-[(piperidin-4-yl)methyl]-1H-benzotriazole

Homo sapiens

37°C, pH 6.40

-

0.04565

6-(1H-indol-3-yl)-1-[(pyrrolidin-3-yl)methyl]-1H-benzotriazole

Homo sapiens

37°C, pH 6.42

-

0.0526

6-(1H-indol-3-yl)-1-[2-(morpholin-4-yl)ethyl]-1H-benzotriazole

Homo sapiens

37°C, pH 6.38

-

0.0052

6-(1H-indol-3-yl)-1-[2-(piperazin-1-yl)ethyl]-1H-benzotriazole

Homo sapiens

37°C, pH 6.45

-

0.002 - 0.00602

6-(1H-indol-3-yl)-1H-benzotriazole

show

-

0.01306

6-(1H-indol-3-yl)-2-methyl-2H-[1,2,3]triazolo[4,5-b]pyridine

Homo sapiens

37°C, pH 6.19

-

0.00783

6-(1H-indol-3-yl)-3-methyl-3H-[1,2,3]triazolo[4,5-b]pyridine

Homo sapiens

37°C, pH 6.20

-

0.0049 - 0.0066

6-(1H-indol-3-yl)isoquinoline

Homo sapiens

37°C, pH 6.7

-

0.0128 - 0.0169

6-(1H-indol-3-yl)quinazoline

Homo sapiens

37°C, pH 6.8

-

0.0017

6-bromo-1H-indazol-4-amine

Homo sapiens

22°C, pH 6.5

-

0.00086

6-bromo-N-(cyclohexylmethyl)-1H-indazol-4-amine

Homo sapiens

22°C, pH 6.5

-

0.00204

6-bromo-N-[(1,4-dioxaspiro[4.5]decan-6-yl)methyl]-1H-indazol-4-amine

Homo sapiens

22°C, pH 6.5

-

0.05841

6-bromo-N-[(1R,2R)-2-hydroxycyclohexyl]-1H-indazole-4-carboxamide

Homo sapiens

22°C, pH 6.5

-

0.00311

6-bromo-N-[(pyridin-2-yl)methyl]-1H-indazol-4-amine

Homo sapiens

22°C, pH 6.5

-

0.01044

6-bromo-N-[(pyrrolidin-3-yl)methyl]-1H-indazol-4-amine

Homo sapiens

22°C, pH 6.5

-

0.00022

6-bromo-N-[[(1S,2S)-2-chlorocyclohexyl]methyl]-1H-indazol-4-amine

Homo sapiens

22°C, pH 6.5

-

0.00185

6-bromo-N-[[(2R)-piperidin-2-yl]methyl]-1H-indazol-4-amine

Homo sapiens

22°C, pH 6.5

-

0.00745

6-bromo-N-[[(2R)-pyrrolidin-2-yl]methyl]-1H-indazol-4-amine

Homo sapiens

22°C, pH 6.5

-

0.00606

6-bromo-N-[[(2S)-piperidin-2-yl]methyl]-1H-indazol-4-amine

Homo sapiens

22°C, pH 6.5

-

0.00417

6-bromo-N-[[(2S)-pyrrolidin-2-yl]methyl]-1H-indazol-4-amine

Homo sapiens

22°C, pH 6.5

-

0.0061 - 0.0087

6-fluoro-3-[(E)-2-(1H-tetrazol-5-yl)ethenyl]-1H-indole

Homo sapiens

37°C, pH 6.5

-

0.0127 - 0.0229

7-(1H-indol-3-yl)-3,4-dihydroquinazolin-2(1H)-one

Homo sapiens

37°C, pH 6.10

-

0.0056 - 0.0071

7-(1H-indol-3-yl)isoquinoline

Homo sapiens

37°C, pH 6.6

-

0.0212 - 0.0326

7-(1H-indol-3-yl)quinazoline

Homo sapiens

37°C, pH 6.9

-

0.00602

8-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indolo[2,1-b]quinazoline-6,12-dione

Homo sapiens

pH and temperature not specified in the publication

-

0.00113

8-fluoro-2-[(1H-1,2,3-triazol-1-yl)methyl]indolo[2,1-b]quinazoline-6,12-dione

Homo sapiens

pH and temperature not specified in the publication

-

0.00006

8-fluoro-6,12-dioxo-6,12-dihydroindolo[2,1-b]quinazoline-2-carbaldehyde

Homo sapiens

pH and temperature not specified in the publication

-

0.00037

ethyl (2E)-3-(8-fluoro-6,12-dioxo-6,12-dihydroindolo[2,1-b]quinazolin-2-yl)prop-2-enoate

Homo sapiens

pH and temperature not specified in the publication

-

0.00287

methyl 1-[(8-fluoro-6,12-dioxo-6,12-dihydroindolo[2,1-b]quinazolin-2-yl)methyl]piperidine-3-carboxylate

Homo sapiens

pH and temperature not specified in the publication

-

0.00099

methyl 1-[(8-fluoro-6,12-dioxo-6,12-dihydroindolo[2,1-b]quinazolin-2-yl)methyl]piperidine-4-carboxylate

Homo sapiens

pH and temperature not specified in the publication

-

0.0003

methyl 1-[(8-fluoro-6,12-dioxo-6,12-dihydroindolo[2,1-b]quinazolin-2-yl)methyl]prolinate

Homo sapiens

pH and temperature not specified in the publication

-

0.01259

methyl 4-([[(1S,2R)-2-hydroxycyclohexyl]methyl]amino)-1H-indazole-6-carboxylate

Homo sapiens

22°C, pH 6.5

-

0.00777

N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-[[2-(sulfamoylamino)ethyl]amino]-1,2,5-oxadiazole-3-carboximidamide

Homo sapiens

22°C, pH 6.5

-

0.00045

N-(4-[[(6-bromo-1H-indazol-4-yl)amino]methyl]cyclohexylidene)hydroxylamine

Homo sapiens

22°C, pH 6.5

-

0.00019

N-methyl-4-phenyl-1,2-oxazol-5-amine

Homo sapiens

pH and temperature not specified in the publication

-

0.04487

N-[(azetidin-3-yl)methyl]-6-bromo-1H-indazol-4-amine

Homo sapiens

22°C, pH 6.5

-

0.00036

N-[[(1S,2R)-2-aminocyclohexyl]methyl]-6-bromo-1H-indazol-4-amine

Homo sapiens

22°C, pH 6.5

-

0.00091

N-[[(1S,2S)-2-aminocyclohexyl]methyl]-6-bromo-1H-indazol-4-amine

Homo sapiens

22°C, pH 6.5

-

0.00136

tert-butyl 3-[[(6-bromo-1H-indazol-4-yl)amino]methyl]pyrrolidine-1-carboxylate

Homo sapiens

22°C, pH 6.5

-

0.1738

[5-(1H-indol-3-yl)-1H-benzotriazol-1-yl]acetic acid

Homo sapiens

37°C, pH 6.29

-

0.1045

[6-(1H-indol-3-yl)-1H-benzotriazol-1-yl]acetic acid

Homo sapiens

37°C, pH 6.30

-

additional information

additional information

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Release 2023.1 (January 2023)