1.13.11.27: 4-hydroxyphenylpyruvate dioxygenase

This is an abbreviated version, for detailed information about 4-hydroxyphenylpyruvate dioxygenase, go to the full flat file.

Reaction

4-hydroxyphenylpyruvate
+
O2
=
homogentisate
+
CO2

Synonyms

4-HPPD, 4-hydroxyphenylpyruvare dioxygenase, 4-hydroxyphenylpyruvate dioxygenase, 4-hydroxyphenylpyruvic acid dioxygenase, 4HPPD, At-HPPD, AtHPPD, AvHPPD-03, EC 1.14.2.2, EC 1.99.1.14, formerly, F Alloantigen, F protein, F-antigen homolog, HPD, hpdA, HPPD, HPPDase, Legiolysin, MsHPPD, oxygenase, 4-hydroxyphenylpyruvate di-, p-hydroxyphenyl pyruvate dioxygenase, p-hydroxyphenylpyruvate dioxygenase, p-hydroxyphenylpyruvate hydroxylase, p-hydroxyphenylpyruvate oxidase, p-hydroxyphenylpyruvic acid hydroxylase, p-hydroxyphenylpyruvic hydroxylase, p-hydroxyphenylpyruvic oxidase, PTO1369, Pt_Hpd, T-cell reactive protein, TF-AG, YS103B

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.27 4-hydroxyphenylpyruvate dioxygenase

Substrates Products

Substrates Products on EC 1.13.11.27 - 4-hydroxyphenylpyruvate dioxygenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2-fluoro-4-hydroxyphenyl)pyruvate + O2
(3-fluoro-2,5-dihydroxyphenyl)pyruvate + CO2
show the reaction diagram
(4-hydroxyphenyl)-pyruvate + O2
homogentisate + CO2
show the reaction diagram
-
-
-
-
?
2-thienylpyruvate + O2
? + CO2
show the reaction diagram
-
-
-
-
?
3,4-dihydroxyphenylpyruvate + O2
? + CO2
show the reaction diagram
3-thienylpyruvate + O2
3-carboxymethyl-3-thiolene-2-one + CO2
show the reaction diagram
-
-
-
?
4-fluorophenylpyruvate + O2
4-fluoro-2-hydroxyphenylacetate + CO2
show the reaction diagram
-
-
-
-
?
4-hydroxyphenylpyruvate + O2
2,5-dihydroxyphenylacetate + CO2
show the reaction diagram
-
-
-
?
4-hydroxyphenylpyruvate + O2
homogentisate + CO2
show the reaction diagram
4-hydroxyphenylpyruvate + O2
homogentisate + CO2 + 4-hydroxyphenylacetate
show the reaction diagram
4-hydroxytetrafluorophenylpyruvate + O2
? + CO2
show the reaction diagram
-
-
-
-
?
4-methylphenylpyruvate + O2
? + CO2
show the reaction diagram
-
poor substrate
-
-
?
phenylpyruvate + O2
2-hydroxyphenylacetate + CO2
show the reaction diagram
[(4-hydroxyphenyl)thio]pyruvate + O2
[(4-hydroxyphenyl)sulfinyl]acetate + CO2
show the reaction diagram
additional information
?
-