1.13.11.3: protocatechuate 3,4-dioxygenase

This is an abbreviated version!
For detailed information about protocatechuate 3,4-dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.3

Reaction

3,4-dihydroxybenzoate
+
O2
=
3-carboxy-cis,cis-muconate

Synonyms

3,4-PCase, 3,4-PCD, 3,4-PCDase, 3,4-POD, EC 1.13.1.3, EC 1.99.2.3, More, oxygenase, protocatechuate 3,4-di-, P3,4DO, P3,4O enzyme, P34O, PCA 3,4-dioxygenase, PcaG, PcaH, PcaHG, protocatchetuate 3,4-dioxygenase, protocatechuate 3,4-dioxygenase, protocatechuate oxygenase, protocatechuic 3,4-dioxygenase, protocatechuic 3,4-oxygenase, protocatechuic acid oxidase

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.3 protocatechuate 3,4-dioxygenase

pH Range

pH Range on EC 1.13.11.3 - protocatechuate 3,4-dioxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2.2 - 13
glyoxyl agarose-immobilized enzyme, profile overview
4 - 14
calcium alginate-immobilized enzyme, profile overview
4 - 9
-
activity range, profile overview
5.5 - 8.5
the enzyme shows more than 50% activity between pH 5.5 and 8.5
6 - 9
-
pH 6.0: about 40% of maximal activity, pH 9.0: about 65% of maximal activity
6.5 - 11.5
free enzyme, profile overview
6.5 - 8
-
80% of maximal activity within this range
7 - 11
the enzyme shows more than 50% activity between pH 7.0 and 11.0 and loses 98.3% of its original enzymatic activity at pH 4.0 and about 95.4% at pH 12.0
additional information
-
activity increases steadily up to pH 9.0, above pH 9.0 the enzyme begins to undergo spontaneous oxidation