1.13.11.48: 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase
This is an abbreviated version!
For detailed information about 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase, go to the full flat file.
Reaction
Synonyms
1H-3-Hydroxy-4-oxoquinaldine 2,4-dioxygenase, 1H-3-hydroxy-4-oxoquinaldine oxygenase, 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase, HOD, HodC, More
ECTree
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Substrates Products
Substrates Products on EC 1.13.11.48 - 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase
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REACTION DIAGRAM
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cleavage of substrate, involved in quinalidine (2-methylquinoline) degradation
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1H-3-hydroxy-4-oxoquinaldine + O2
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cleavage of substrate, involved in quinalidine (2-methylquinoline) degradation
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?
N-Acetylanthranilate + CO
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?
1H-3-Hydroxy-4-oxoquinaldine + O2
N-Acetylanthranilate + CO
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?
1H-3-Hydroxy-4-oxoquinaldine + O2
N-Acetylanthranilate + CO
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?
1H-3-Hydroxy-4-oxoquinaldine + O2
N-Acetylanthranilate + CO
Hod has adapted active-site residues of the alpha/beta hydrolase fold for the dioxygenolytic reaction
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?
1H-3-Hydroxy-4-oxoquinaldine + O2
N-Acetylanthranilate + CO
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?
1H-3-Hydroxy-4-oxoquinaldine + O2
N-Acetylanthranilate + CO
Hod has adapted active-site residues of the alpha/beta hydrolase fold for the dioxygenolytic reaction
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?
1H-3-Hydroxy-4-oxoquinaldine + O2
N-Acetylanthranilate + CO
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?
1H-3-Hydroxy-4-oxoquinaldine + O2
N-Acetylanthranilate + CO
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-
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?
1H-3-Hydroxy-4-oxoquinaldine + O2
N-Acetylanthranilate + CO
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-
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?
1H-3-Hydroxy-4-oxoquinaldine + O2
N-Acetylanthranilate + CO
Hod has adapted active-site residues of the alpha/beta hydrolase fold for the dioxygenolytic reaction
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-
?
1H-3-Hydroxy-4-oxoquinaldine + O2
N-Acetylanthranilate + CO
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?
1H-3-hydroxy-4-oxoquinaldine + O2
N-acetylanthranilic acid + CO
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1H-3-hydroxy-4-oxoquinaldine oxygenase
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ir
1H-3-hydroxy-4-oxoquinaldine + O2
N-acetylanthranilic acid + CO
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1H-3-hydroxy-4-oxoquinaldine oxygenase
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ir
1H-3-hydroxy-4-oxoquinaldine + O2
N-acetylanthranilic acid + CO
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1H-3-hydroxy-4-oxoquinaldine oxygenase
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ir
1H-3-hydroxy-4-oxoquinaldine + O2
N-acetylanthranilic acid + CO
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1H-3-hydroxy-4-oxoquinaldine oxygenase
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ir
1H-3-hydroxy-4-oxoquinaldine + O2
N-acetylanthranilic acid + CO
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?
1H-3-hydroxy-4-oxoquinaldine + O2
N-acetylanthranilic acid + CO
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?
1H-3-hydroxy-4-oxoquinaldine + O2
N-acetylanthranilic acid + CO
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?
N-formylanthranilic acid + CO
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ir
1H-3-hydroxy-4-oxoquinoline + O2
N-formylanthranilic acid + CO
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ir
1H-3-hydroxy-4-oxoquinoline + O2
N-formylanthranilic acid + CO
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also 1H-3-hydroxy-4-oxoquinaldine oxygenase
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ir
1H-3-hydroxy-4-oxoquinoline + O2
N-formylanthranilic acid + CO
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also 1H-3-hydroxy-4-oxoquinaldine oxygenase
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ir
1H-3-hydroxy-4-oxoquinoline + O2
N-formylanthranilic acid + CO
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ir
N-formylanthranilate + CO
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?
3-hydroxy-1H-quinoline-4-one + O2
N-formylanthranilate + CO
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?
N-acetylanthranilate + CO
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?
3-hydroxy-2-methyl-1H-quinolin-4-one + O2
N-acetylanthranilate + CO
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?
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absence of viscosity effects and kinetic solvent isotope effects suggests that turnover of the ternary complex, rather than substrate binding, product release, or proton movements, involves the rate-determining step in the reaction catalyzed by Hod
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?
additional information
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absence of viscosity effects and kinetic solvent isotope effects suggests that turnover of the ternary complex, rather than substrate binding, product release, or proton movements, involves the rate-determining step in the reaction catalyzed by Hod
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-
?
additional information
?
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absence of viscosity effects and kinetic solvent isotope effects suggests that turnover of the ternary complex, rather than substrate binding, product release, or proton movements, involves the rate-determining step in the reaction catalyzed by Hod
-
-
?