1.13.11.52: indoleamine 2,3-dioxygenase

This is an abbreviated version!
For detailed information about indoleamine 2,3-dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.52

Reaction

D-tryptophan
+
O2
=
N-formyl-D-kynurenine

Synonyms

31854, BRAFLDRAFT_126354, CG5163, EC 1.11.1.4, EC 1.13.1.12, hIDO, hIDO1, hTDO, IDO, IDO-1, IDO-2, IDO1, IDO2, INDO, INDOL1, indolamine 2,3-dioxygenase, indole 2,3-dioxygenase, indoleamine 2, 3-dioxygenase, indoleamine 2,3 dioxygenase, indoleamine 2,3-dioxygenase, indoleamine 2,3-dioxygenase 1, indoleamine 2,3-dioxygenase 2, indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2, indoleamine 2,3-dioxygenase-like protein, indoleamine-2,3-dioxygenase, Indoleamine-pyrrole 2,3-dioxygenase, L-tryptophan 2,3-dioxygenase, L-tryptophan pyrrolase, mIDO, oxygenase, tryptophan 2,3-di-, proto-IDO, proto-indoleamine 2,3-dioxygenase, superoxygenase, TDO, TDO2, TioF, TO, TRPO, Tryptamin 2,3-dioxygenase, tryptamine 2,3-dioxygenase, tryptophan 2,3-dioxygenase, tryptophan dioxygenase, tryptophan oxygenase, tryptophan peroxidase, tryptophan pyrrolase, tryptophan-2,3-dioxygenase, tryptophanase, v1g244579, Vermilion protein

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.52 indoleamine 2,3-dioxygenase

Molecular Weight

Molecular Weight on EC 1.13.11.52 - indoleamine 2,3-dioxygenase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
105000
-
enzyme from intestine, gel filtration
118000
-
high speed equilibrium sedimentation
120000
122000
-
gel filtration, sucrose density gradient centrifugation, equilibrium sedimentation
123000
-
low speed equilibrium sedimentation
150000
-
alpha2beta2 subunit
16000
-
enzyme from skin, gel filtration
160000 - 180000
-
gel filtration, sucrose density gradient centrifugation
167000
190000
27000
-
4 * 27000, SDS-PAGE
31000
-
4 * 31000, SDS-PAGE
320000
-
gel filtration, liver
40000
-
1 * 40000, SDS-PAGE
41000
-
1 * 41000, sedimentation velocity experiments in presence of 6 M guanidine HCl
42000
43000
44800
-
x * 44800, calculated from sequence
45000
45200
-
isozyme IDO2, calculated from amino acid sequence
45300
-
isozyme IDO1, calculated from amino acid sequence
45440
-
ESI mass spectrometry
45639
x * 45639, calculation from nucleotide sequence
46980
-
ESI mass spectrometry
47000
-
x * 47000, about, IDO2, SDS-PAGE
47796
4 * 47796, calculation from nucleotide sequence
47900
-
x * 47900, SDS-PAGE
54000
-
gel filtration
additional information