1.13.11.54: acireductone dioxygenase [iron(II)-requiring]

This is an abbreviated version!
For detailed information about acireductone dioxygenase [iron(II)-requiring], go to the full flat file.

Reaction

Synonyms

1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, aci-reductone dioxygenase, acireductone dioxygenase, acireductone dioxygenase 1, ADI1, ARD, ARD', ARD1, ARD4, ARDp, Fe(II)-bound acireductone dioxygenase, Fe-ARD, MTCBP-1, MtnD, OsARD1, Ymr009p

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.11 With incorporation of two atoms of oxygen

                1.13.11.54 acireductone dioxygenase [iron(II)-requiring]

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Results	in table
1	Activating Compound
8138	AA Sequence
1	Application
2	CAS Registry Number
11	Cloned(Commentary)
4	Crystallization (Commentary)
24	Disease/ Diagnostics
2	Expression
12	General Information
1	kcat/KM [mM/s]
7	KM Value [mM]
2	Localization
17	Metals/Ions
5	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
22	Organism
5	Pathway
10	PDB ID
1	pI Value
20	Protein Variants
7	Purification (Commentary)
1	Reaction
4	Reaction Type
22	Reference
9	Source Tissue
27	Substrates and Products (Substrate)
7	Subunits
27	Synonyms
1	Systematic Name
3	Temperature Stability [°C]
5	Turnover Number [1/s]

Disease

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Disease on EC 1.13.11.54 - acireductone dioxygenase [iron(II)-requiring]

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Brain Neoplasms

Evidence of MTCBP-1 interaction with the cytoplasmic domain of MT1-MMP: Implications in the autophagy cell index of high-grade glioblastoma.

25640948

Glioblastoma

Evidence of MTCBP-1 interaction with the cytoplasmic domain of MT1-MMP: Implications in the autophagy cell index of high-grade glioblastoma.

25640948

Hepatitis C

Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors.

14718544

Neoplasm Metastasis

Alterations of metastasis-related genes identified using an oligonucleotide microarray of genistein-treated HCC1395 breast cancer cells.

17640171

Neoplasm Metastasis

Pancreatic tumor cell metastasis is restricted by MT1-MMP binding protein MTCBP-1.

30487181

Neoplasms

Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors.

14718544

Neoplasms

Pancreatic tumor cell metastasis is restricted by MT1-MMP binding protein MTCBP-1.

30487181

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