1.13.11.57: gallate dioxygenase

This is an abbreviated version, for detailed information about gallate dioxygenase, go to the full flat file.

Reaction

gallate
+
O2
=
(1E)-4-oxobut-1-ene-1,2,4-tricarboxylate

Synonyms

DesB, GA dioxygenase, GALA

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.57 gallate dioxygenase

Inhibitors

Inhibitors on EC 1.13.11.57 - gallate dioxygenase

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,2'-dipyridyl
-
2 mM 2,2'-dipyridyl, a specific Fe2+-chelator, abolishes the gallate dioxygenase activity completely
H2O2
-
hydrogen peroxide at 1 mM reduces the gallate dioxygenase activity to 15%, and the activity can be partially restored (50% activity of the untreated enzyme) upon addition of 10 mM ascorbate