1.13.11.60: linoleate 8R-lipoxygenase

This is an abbreviated version!
For detailed information about linoleate 8R-lipoxygenase, go to the full flat file.

Word Map on EC 1.13.11.60

Reaction

linoleate
+
O2
=
(8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate

Synonyms

5,8-LDS, 5,8-linoleate diol synthase, 5,8-linoleate diol synthases, 7,8-diol synthase, 7,8-LDS, 7,8-linoleate diol synthase, 8(R)-dioxygenase, 8,11-hydroperoxide isomerase, 8-DOX, 8R-dioxygenase, 8R-DOX, dioxygenase-cytochrome P450, DOX-CYP, FOXB_09952, GLRG_10013, linoleate 7,8-LDS, linoleate 8,11-LDS, linoleate diol synthase, linoleic acid 8R-dioxygenase, orphan DOX-CYP, PpoA

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.60 linoleate 8R-lipoxygenase

General Information

General Information on EC 1.13.11.60 - linoleate 8R-lipoxygenase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
malfunction
replacements of Tyr and Cys in the conserved YRWH and FXXGPHXCLG sequences abolished 8R-dioxygenase and hydroperoxide isomerase activities, respectively
metabolism
additional information