1.13.11.75: all-trans-8'-apo-beta-carotenal 15,15'-oxygenase
This is an abbreviated version!
For detailed information about all-trans-8'-apo-beta-carotenal 15,15'-oxygenase, go to the full flat file.
Word Map on EC 1.13.11.75
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1.13.11.75
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apocarotenoids
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oxygenases
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synechocystis
-
non-heme
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stilbene
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nceds
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zeaxanthin
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strigolactone
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all-trans-retinyl
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piceatannol
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4-vinylguaiacol
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end-groups
- 1.13.11.75
-
apocarotenoids
- oxygenases
- synechocystis
-
non-heme
- stilbene
-
nceds
- zeaxanthin
- strigolactone
-
all-trans-retinyl
- piceatannol
- 4-vinylguaiacol
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end-groups
Reaction
Synonyms
ACO, apo-carotenoid oxygenase, apocarotenoid cleavage oxygenase, apocarotenoid oxygenase, apocarotenoid-15,15'-oxygenase, apocarotenoid-15-15'-oxygenase, carotenoid cleavage oxygenase, CCO, Diox1, EC 1.14.99.41, More, sll1541
ECTree
1.13.11.75 all-trans-8'-apo-beta-carotenal 15,15'-oxygenaseAdvanced search results
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results (Results
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19
Substrates Products
Substrates Products on EC 1.13.11.75 - all-trans-8'-apo-beta-carotenal 15,15'-oxygenase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(3R)-3hydroxy-beta-apo-12'-carotenal + O2
(3R)-3-hydroxy-retinal + ?
-
-
-
?
(3R)-3hydroxy-beta-apo-12'-carotenal + O2
(3R)-3-hydroxyretinal + ?
-
-
-
?
(3R)-3hydroxy-beta-apo-8'-carotenal + O2
(3R)-3-hydroxy-retinal + apo-8',15'-apo-carotenedial
-
-
-
?
(3R)-3hydroxy-beta-apo-8'-carotenal + O2
(3R)-3-hydroxyretinal + apo-8',15'-apo-carotenedial
-
-
-
?
(3R)-3hydroxy-beta-apo-8'-carotenol + O2
(3R)-3-hydroxy-retinal + apo-8',15'-apo-carotenedial
-
-
-
?
(3R)-3hydroxy-beta-apo-8'-carotenol + O2
(3R)-3-hydroxyretinal + apo-8',15'-apo-carotenedial
-
-
-
?
3-hydroxy-beta-apo-10'-carotenal + O2
?
3% cleavage at C15-C15' double bond, 97% cleavage at the C13-C14 double bond
-
-
?
3-hydroxy-beta-apo-8'-carotenal + O2
?
95% cleavage at C15-C15' double bond, 5% cleavage at the C13-C14 double bond
-
-
?
all-trans-(3R)-hydroxy-8'-apo-beta-carotenol + O2
?
-
-
-
?
all-trans-8'-apo-beta-carotenal + O2
all-trans-retinal + 8'-hydroxy-15'-apocarotenal
-
-
-
?
all-trans-8'-apo-beta-carotenol + O2
all-trans-retinal + (2E,4E,6E)-8-hydroxy-2,6-dimethylocta-2,4,6-trienal
-
-
-
?
all-trans-8'-apocarotenol + O2
all-trans-retinal + (2E,4E,6E)-8-hydroxy-2,6-dimethylocta-2,4,6-trienal
-
-
-
?
all-trans-beta-apo-8'-carotenal + O2
all-trans-retinal + apo-8'15'-apo-carotenedial
the cis-isomer is not a substrate
-
-
?
beta-apo-8'-carotenal + O2
retinal + apo-8',15'-apo-carotenedial
-
-
-
?
beta-carotene + O2
retinal + beta-apo-14'-carotenal + beta-apo-13-carotenone
30% cleavage at C13-C14 double bond, 69% cleavage at the C15-C15' double bond
-
-
?
lutein + O2
?
54% cleavage at C15-C15' double bond, 45% cleavage at the C13-C14 double bond
-
-
?
3,3'-dihydoxyisorenieratene + O2
?
54% cleavage at C15-C15' double bond, 45% cleavage at the C13-C14 double bond
-
-
?
3,3'-dihydoxyisorenieratene + O2
?
54% cleavage at C15-C15' double bond, 45% cleavage at the C13-C14 double bond
-
-
?
beta-apo-10'-carotenal + O2
?
79% cleavage at C13-C14 double bond, 20% cleavage at the C15-C15' double bond
-
-
?
beta-apo-10'-carotenal + O2
?
79% cleavage at C13-C14 double bond, 20% cleavage at the C15-C15' double bond
-
-
?
beta-apo-8'-carotenal + O2
?
86% cleavage at C13-C14 double bond, 14% cleavage at the C15-C15' double bond
-
-
?
beta-apo-8'-carotenal + O2
?
86% cleavage at C13-C14 double bond, 14% cleavage at the C15-C15' double bond
-
-
?
beta-apo-8'-carotenol + O2
retinal + apo-8',15'-apo-carotenedial
-
-
-
?
beta-apo-8'-carotenol + O2
retinal + apo-8',15'-apo-carotenedial
-
-
-
?
zeaxanthin + O2
?
83% cleavage at C15-C15' double bond, 17% cleavage at the C13-C14 double bond
-
-
?
zeaxanthin + O2
?
83% cleavage at C15-C15' double bond, 17% cleavage at the C13-C14 double bond
-
-
?
additional information
?
-
MtCCO cleaves the central C15-C15' and an excentric double bond at the C13-C14 position. The preference for each of the cleavage positions is determined by the hydroxylation and the nature of the ionone ring
-
-
?
additional information
?
-
-
MtCCO cleaves the central C15-C15' and an excentric double bond at the C13-C14 position. The preference for each of the cleavage positions is determined by the hydroxylation and the nature of the ionone ring
-
-
?
additional information
?
-
MtCCO cleaves the central C15-C15' and an excentric double bond at the C13-C14 position. The preference for each of the cleavage positions is determined by the hydroxylation and the nature of the ionone ring
-
-
?
additional information
?
-
enzyme exhibits a wide substrate specificity with respect to chain lengths and functional endgroups, converting beta-apo-carotenals, (3R)-3-hydroxy-beta-apocarotenals and the corresponding alcohols into retinal and (3R)-3-hydroxyretinal, respectively. Cleavage occurs at the C15-C15' double bond. No substrates: beta-apo-4'-carotenal, beta-apo-12'-carotenal
-
-
?
additional information
?
-
-
the substrate specificity of the enzyme is unique in that it cleaves only all-trans apocarotenoids of different chain lengths, but not C40 beta-carotene to yield all-trans C20 retinal or its derivatives
-
-
?
additional information
?
-
enzyme exhibits wide substrate specificity with respect to chain-lengths and functional end-groups
-
-
?
additional information
?
-
enzyme ACO exclusively produces all-trans-retinal from all-trans-apo-8'-carotenol. ACO cleaves but does not isomerize all-trans-8'-apocarotenol. Raman spectroscopic study, overview. During the entire reaction, spectroscopic signals for 13-cis-retinal or the 13,14'-di-cis-8-apocarotenol intermediate are not detected
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-
?
