1.13.11.77: oleate 10S-lipoxygenase

This is an abbreviated version!
For detailed information about oleate 10S-lipoxygenase, go to the full flat file.

Reaction

Synonyms

(10S)-dioxygenase, (10S)-DOX, 10-dioxygenase, 10S-dioxygenase, 10S-DOX, 10S-DOX-like lipoxygenase, heme dioxygenase, linoleate 10S-dioxygenase, linoleate 10S-DOX, linoleate heme 10S-dioxygenase, LOX, Np-diox, Npun_R5469, oleate heme 10S-dioxygenase

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.11 With incorporation of two atoms of oxygen

                1.13.11.77 oleate 10S-lipoxygenase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	Activating Compound
2	AA Sequence
2	Cloned(Commentary)
4	General Information
18	Inhibitors
3	kcat/KM [mM/s]
9	KM Value [mM]
3	Localization
3	Metals/Ions
2	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
13	Organism
1	PDB ID
2	pH Optimum
1	Protein Variants
3	Purification (Commentary)
3	Reaction
11	Reference
3	Specific Activity [micromol/min/mg]
1	Storage Stability
32	Substrates and Products (Substrate)
3	Subunits
24	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Stability [°C]
3	Turnover Number [1/s]

Inhibitors

print visible entries

print all entries

Inhibitors on EC 1.13.11.77 - oleate 10S-lipoxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Inhibitor Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

(8,10,12-EEZ)-conjugated linoleic acid derivative

Nostoc punctiforme

-

strong inhibition

744396

alpha-calendic acid

Nostoc punctiforme

-

(8,10,12-ZEE)-conjugated linoleic acid derivative, strong inhibition

744396

alpha-eleostearic acid

Nostoc punctiforme

-

(9,11,13-ZEE)-conjugated linoleic acid derivative, strong inhibition

744396

alpha-linolenic acid

Nostoc punctiforme

-

13% inhibition

744396

Ba2+

Pseudomonas sp.

-

complete inhibition at 1 mM

723962

beta-calendic acid

Nostoc punctiforme

-

(8,10,12-EEE)-conjugated linoleic acid derivative, complete inhibition

744396

beta-eleostearic acid

Nostoc punctiforme

-

(9,11,13-EEE)-conjugated linoleic acid derivative, complete inhibition

744396

catalpic acid

Nostoc punctiforme

-

(9,11,13-EEZ)-conjugated linoleic acid derivative

744396

EDTA

Pseudomonas sp.

-

99% inhibition at 5 mM

723962

Fe3+

Pseudomonas sp.

-

complete inhibition at 1 mM

723962

jacaric acid

Nostoc punctiforme

-

(8,10,12-ZEZ)-conjugated linoleic acid derivative, low inhibition

744396

Mg2+

Pseudomonas sp.

-

concentrations of Mg2+ higher than 1.25 mM inhibit activity strongly (90% of activity lost at 1.75 mM)

723962

oleate

Pseudomonas sp.

-

at concentrations of oleate higher than 2.1 mM, the enzyme activity is inhibited by excess of substrate

723962

oxidized linoleic acid

Nostoc punctiforme

-

6% inhibition

744396

-

punicic acid

Nostoc punctiforme

-

(9,11,13-ZEZ)-conjugated linoleic acid derivative

744396

Zn2+

Pseudomonas sp.

-

complete inhibition at 1 mM

723962

additional information

2 entries

-

additional information

Nostoc punctiforme

-

the enzyme is potently inhibited by 8,10,12- and 9,11,13-conjugated linoleic acid derivatives, found as impurities in the linoleic acid preparation from plant, overview

744396

-

additional information

Pseudomonas sp.

-

not inhibited by 5 mM KCN

723962

-