1.13.11.79: aerobic 5,6-dimethylbenzimidazole synthase
This is an abbreviated version!
For detailed information about aerobic 5,6-dimethylbenzimidazole synthase, go to the full flat file.
Reaction
Synonyms
BluB, bluB/cobT2, DMB-synthase, EC 1.14.99.40, flavin destructase, flavin destructase enzyme
ECTree
1.13.11.79 aerobic 5,6-dimethylbenzimidazole synthaseAdvanced search results
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results (Results
in table
2849
12
20
Engineering
Engineering on EC 1.13.11.79 - aerobic 5,6-dimethylbenzimidazole synthase
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PROTEIN VARIANTS 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
D32N
D32N/S167G
site-directed mutagenesis, the mutant shows no activity
G110S
site-directed mutagenesis, the mutant shows no 5,6-dimethylbenzimidazole forming activity
G133S
site-directed mutagenesis, the mutant shows no 5,6-dimethylbenzimidazole forming activity
G61D
M140I
site-directed mutagenesis, the mutant shows highly reduced activity compared to the wild-type enzyme
M94I
P202L
site-directed mutagenesis, the mutant shows no 5,6-dimethylbenzimidazole forming activity
R30C
site-directed mutagenesis, the mutant shows no 5,6-dimethylbenzimidazole forming activity
R30H
site-directed mutagenesis, the mutant shows no 5,6-dimethylbenzimidazole forming activity
S167G
D32N
site-directed mutagenesis, the mutant shows highly reduced activity compared to the wild-type enzyme
D32N
-
the mutant is specifically impaired in the flavin destruction phase of the reaction of the wild type enzyme
G61D
site-directed mutagenesis, the mutant shows no 5,6-dimethylbenzimidazole forming activity
M94I
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
S167G
site-directed mutagenesis, the mutant shows higly reduced activity compared to the wild-type enzyme
S167G
-
the mutant is specifically impaired in the flavin destruction phase of the reaction of the wild type enzyme
