1.13.11.81: 7,8-dihydroneopterin oxygenase
This is an abbreviated version!
For detailed information about 7,8-dihydroneopterin oxygenase, go to the full flat file.
Word Map on EC 1.13.11.81
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1.13.11.81
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anger
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downey
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robot
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hemiplegic
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davison
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waddington
- 1.13.11.81
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anger
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downey
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robot
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hemiplegic
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davison
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waddington
Reaction
Synonyms
DHNA, dihydroneopterin oxygenase, Rv3607c, Y53F mutant of dihydroneopterin aldolase, Y54F mutant of dihydroneopterin aldolase
ECTree
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Engineering
Engineering on EC 1.13.11.81 - 7,8-dihydroneopterin oxygenase
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Y53F
the substitution of a conserved tyrosine residue at the active site of dihydroneopterin aldolase by phenylalanine converts the enzyme to a cofactor-independent oxygenase, which generates mainly 7,8-dihydroxanthopterin rather than 6-hydroxymethyl-7,8-dihydropterin
Y54F
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the substitution of a conserved tyrosine residue at the active site of dihydroneopterin aldolase by phenylalanine converts the enzyme to a cofactor-independent oxygenase, which generates mainly 7,8-dihydroxanthopterin rather than 6-hydroxymethyl-7,8-dihydropterin