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1.13.11.86: 5-aminosalicylate 1,2-dioxygenase

This is an abbreviated version!
For detailed information about 5-aminosalicylate 1,2-dioxygenase, go to the full flat file.

Reaction

5-Aminosalicylate
+
O2
=
(2Z,4E)-4-amino-6-oxohepta-2,4-dienedioate

Synonyms

5AS 1,2-dioxygenase, mabB

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.86 5-aminosalicylate 1,2-dioxygenase

Systematic Name

Systematic Name on EC 1.13.11.86 - 5-aminosalicylate 1,2-dioxygenase

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SYSTEMATIC NAME
IUBMB Comments
5-aminosalicylate:oxygen 1,2-oxidoreductase (ring-opening)
Requires Fe(II). The enzyme, characterized from different bacteria, is a nonheme iron dioxygenase in the bicupin family.