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1.13.11.87: endo-cleaving rubber dioxygenase

This is an abbreviated version!
For detailed information about endo-cleaving rubber dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.87

Reaction

Cleavage of cis-1,4-polyisoprene polymers into a mixture of compounds, including a C20 compound ((4Z,8Z,12Z,16Z,20Z,24Z)-4,8,12,16,20,24-hexamethyl-28-oxononacosa-4,8,12,16,20,24-hexaenal), a C25 compound ((4Z,8Z,12Z,16Z,20Z)-4,8,12,16,20-pentamethyl-24-oxopentacosa-4,8,12,16,20-pentaenal), a C30 compound ((4Z,8Z,12Z,16Z)-4,8,12,16-tetramethyl-20-oxohenicosa-4,8,12,16-tetraenal), and larger isoprenologes such as C35, C40, C45, and higher analogues =

Synonyms

GPOL_174p00150, GPOL_c48310, latex clearing protein, latex-clearing protein, Lcp, Lcp protein, Lcp1, lcp1VH2, Lcp2, lcp2VH2, LcpK30, polyisoprene-cleaving rubber oxygenase, roxA, RoxB, rubber oxidizing protein, rubber oxygenase, rubber oxygenase B

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.87 endo-cleaving rubber dioxygenase

Inhibitors

Inhibitors on EC 1.13.11.87 - endo-cleaving rubber dioxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
1 mM, 20% inhibition
2,2'-bipyridyl
-
15% residual activity at 10 mM
alpha-tocopherol
1 mM, 40% inhibition
ascorbate
1 mM, 20% inhibition
carotene
1 mM, 40% inhibition
CO
oxygen consumption by RoxB is inhibited when carbon monoxide is added to an ongoing polyisoprene cleavage reaction
Diethyl dithiocarbamate
diethyldithiocarbamate
Diethylthiocarbamate
1 mM, 56% inhibition
disodium 4,5-dihydroxy-1,3-benzenedisulfonate
-
45% residual activity at 10 mM
-
Dithionite
1 mM, 15% inhibition
dithiothreitol
10 mM, 90% inhibition
ethanol
5%, 10% inhibition
ethyl acetate
the presence of ethyl acetate does not completely inhibit the activity of the enzyme
ethyl xanthogenate
1 mM, 7% inhibition
ethylxanthate
-
46% residual activity at 10 mM
imidazole
pentane
the presence of pentane does not completely inhibit the activity of the enzyme
Phenanthroline
Pyridine
squalene
1 mM, 10% inhibition
additional information
-