1.13.12.13: Oplophorus-luciferin 2-monooxygenase

This is an abbreviated version!
For detailed information about Oplophorus-luciferin 2-monooxygenase, go to the full flat file.

Word Map on EC 1.13.12.13

Reaction

Oplophorus luciferin
+
O2
=
oxidized Oplophorus luciferin
+
CO2
+
hnu

Synonyms

19kOLase, imidazopyrazinone-type luciferase, KAZ, luciferase, nanoKAZ, NanoLuc, Oluc-19, Oplophorus luciferase

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
                1.13.12.13 Oplophorus-luciferin 2-monooxygenase

Reference

Reference on EC 1.13.12.13 - Oplophorus-luciferin 2-monooxygenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Yamaguchi, I.
Oplophorus oxyluciferin and a model luciferin compound biologically active with Oplophorus luciferase
Biochem. J.
151
9-15
1975
Oplophorus gracilirostris
Manually annotated by BRENDA team
Nakamura, H.; Wu, C.; Murai, A.; Inouye, S.; Shimomura, O.
Efficient bioluminescence of bisdeoxycoelenterazine with the luciferase of a deep-sea shrimp Oplophorus
Tetrahedron Lett.
38
6405-6406
1997
Oplophorus gracilirostris
-
Manually annotated by BRENDA team
Kakoi, H.; Okada, K.
Chemical studies of fish bioluminescence
ITE Lett. Batteries New Technol. Med.
6
38-45
2005
Diaphus gigas
-
Manually annotated by BRENDA team
Inouye, S.; Sasaki, S.
Overexpression, purification and characterization of the catalytic component of Oplophorus luciferase in the deep-sea shrimp, Oplophorus gracilirostris
Protein Expr. Purif.
56
261-268
2007
Oplophorus gracilirostris
Manually annotated by BRENDA team
Inouye, S.; Sahara, Y.
Soluble protein expression in E. coli cells using IgG-binding domain of protein A as a solubilizing partner in the cold induced system
Biochem. Biophys. Res. Commun.
376
448-453
2008
Oplophorus gracilirostris (Q9GV45)
Manually annotated by BRENDA team
Inouye, S.; Sato, J.; Sahara-Miura, Y.; Yoshida, S.; Kurakata, H.; Hosoya, T.
C6-Deoxy coelenterazine analogues as an efficient substrate for glow luminescence reaction of nanoKAZ: the mutated catalytic 19 kDa component of Oplophorus luciferase
Biochem. Biophys. Res. Commun.
437
23-28
2013
Oplophorus gracilirostris
Manually annotated by BRENDA team
Hall, M.P.; Unch, J.; Binkowski, B.F.; Valley, M.P.; Butler, B.L.; Wood, M.G.; Otto, P.; Zimmerman, K.; Vidugiris, G.; Machleidt, T.; Robers, M.B.; Benink, H.A.; Eggers, C.T.; Slater, M.R.; Meisenheimer, P.L.; Klaubert, D.H.; Fan, F.; Encell, L.P.; Wood, K.V.
Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate
Chem. Biol.
7
1848-1857
2012
Oplophorus gracilirostris
Manually annotated by BRENDA team
Inouye, S.; Sahara-Miura, Y.; Sato, J.; Iimori, R.; Yoshida, S.; Hosoya, T.
Expression, purification and luminescence properties of coelenterazine-utilizing luciferases from Renilla, Oplophorus and Gaussia: comparison of substrate specificity for C2-modified coelenterazines
Protein Expr. Purif.
88
150-156
2013
Oplophorus gracilirostris
Manually annotated by BRENDA team
Inouye, S.; Sato, J.; Sahara-Miura, Y.; Yoshida, S.; Hosoya, T.
Luminescence enhancement of the catalytic 19 kDa protein (KAZ) of Oplophorus luciferase by three amino acid substitutions
Biochem. Biophys. Res. Commun.
445
157-162
2014
Oplophorus gracilirostris (Q9GV45 AND Q9GV46)
Manually annotated by BRENDA team
Inouye, S.; Sato, J.; Sahara-Miura, Y.; Hosoya, T.; Suzuki, T.
Unconventional secretion of the mutated 19 kDa protein of Oplophorus luciferase (nanoKAZ) in mammalian cells
Biochem. Biophys. Res. Commun.
450
1313-1319
2014
Oplophorus gracilirostris (Q9GV45 AND Q9GV46)
Manually annotated by BRENDA team
Tomabechi, Y.; Hosoya, T.; Ehara, H.; Sekine, S.; Shirouzu, M.; Inouye, S.
Crystal structure of nanoKAZ The mutated 19kDa component of Oplophorus luciferase catalyzing the bioluminescent reaction with coelenterazine
Biochem. Biophys. Res. Commun.
470
88-93
2016
Oplophorus gracilirostris (Q9GV45 AND Q9GV46)
Manually annotated by BRENDA team