1.13.12.24: calcium-regulated photoprotein

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For detailed information about calcium-regulated photoprotein, go to the full flat file.

Reaction

Synonyms

aequorin, alcium-activated photoprotein, berovin, BFP-aq, blue fluorescent protein, Ca2+-binding photoprotein, Ca2+-regulated photoprotein, clytin, halistaurin, mitrocomin, mnemiopsin, mnemiopsin 1, mnemiopsin 2, mnemiopsin1, obelin, phialidin

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)

                1.13.12.24 calcium-regulated photoprotein

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Results	in table
4	Activating Compound
10	AA Sequence
7	Application
26	Cloned(Commentary)
6	Crystallization (Commentary)
3	General Information
2	General Stability
11	Inhibitors
20	Metals/Ions
6	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
6	Organic Solvent Stability
41	Organism
5	pH Optimum
1	pH Stability
57	Protein Variants
16	Purification (Commentary)
5	Reaction
41	Reference
1	Source Tissue
28	Substrates and Products (Substrate)
6	Subunits
30	Synonyms
1	Systematic Name
13	Temperature Stability [°C]

Reaction

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Reaction on EC 1.13.12.24 - calcium-regulated photoprotein

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REACTION

REACTION DIAGRAM

COMMENTARY

ORGANISM

UNIPROT

LITERATURE

[aequorin] + 3 Ca2+ = [aequorin] 1,2-dioxetan-3-one

(1c)

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[aequorin] 1,2-dioxetan-3-one = [excited state blue fluorescent protein] + CO2

(1d)

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[apoaequorin containing coelenterazine] + O2 = [aequorin]

(1b)

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[apoaequorin] + coelenterazine + O2 + 3 Ca2+ = [excited state blue fluorescent protein] + CO2

overall reaction

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[apoaequorin] + coelenterazine = [apoaequorin containing coelenterazine]

(1a)

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