184.108.40.206: tryptophan 2-monooxygenase
This is an abbreviated version, for detailed information about tryptophan 2-monooxygenase, go to the full flat file.
IaaM, oxygenase, tryptophan 2-mono-, Pgt-IaaM, PGTG_11658, TMO, tryptophan 2-monooxygenase, tryptophan monooxygenase
1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
Advanced search results
Engineering on EC 220.127.116.11 - tryptophan 2-monooxygenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
mutation decreases the kcat and kcat/Km (L-tryptophan) values by 60000- and 2 millionfold compared to wild-type, respectively
mutation decreases the kcat value less than 2fold and the kcat/Km (L-tryptophan) value only 5fold compared to wild-type
mutation results in an enzyme lacking flavin and detectable activity
200fold reduction in first-order rate constant for reduction, 33fold decrease in rate constant for oxidation, conversion of enzyme to oxidase