1.13.12.3: tryptophan 2-monooxygenase

This is an abbreviated version, for detailed information about tryptophan 2-monooxygenase, go to the full flat file.

Reaction

L-tryptophan
+
O2
=
(indol-3-yl)acetamide
+
CO2
+
H2O

Synonyms

IaaM, oxygenase, tryptophan 2-mono-, Pgt-IaaM, PGTG_11658, TMO, tryptophan 2-monooxygenase, tryptophan monooxygenase

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
                1.13.12.3 tryptophan 2-monooxygenase

Expression

Expression on EC 1.13.12.3 - tryptophan 2-monooxygenase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
aniline (stress) stimulates tryptophan/indoles synthesis via the shikimate pathway, including tryptophan 2-monooxygenase activity, by possibly modulating the metabolic pathway
gene IaaM is constitutively expressed and no transcription factor further activates its promoter