1.13.12.3: tryptophan 2-monooxygenase

This is an abbreviated version, for detailed information about tryptophan 2-monooxygenase, go to the full flat file.

Reaction

L-tryptophan
+
O2
=
(indol-3-yl)acetamide
+
CO2
+
H2O

Synonyms

IaaM, oxygenase, tryptophan 2-mono-, Pgt-IaaM, PGTG_11658, TMO, tryptophan 2-monooxygenase, tryptophan monooxygenase

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
                1.13.12.3 tryptophan 2-monooxygenase

KM Value

KM Value on EC 1.13.12.3 - tryptophan 2-monooxygenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.3
D,L-3-phenyl-2-hydrazinopropanoic acid
-
-
32
D,L-3-pyridylalanine
-
-
22.6
D,L-N-methyl-phenylalanine
-
-
22.6
L-alanine
-
-
22.4
L-methionine
-
-
2.4
L-phenylalanine
-
-
0.036 - 1.48
L-tryptophan
0.067 - 140
O2
0.04 - 30
tryptophan