1.13.99.1: inositol oxygenase

This is an abbreviated version!
For detailed information about inositol oxygenase, go to the full flat file.

Reaction

Synonyms

amyoinositol oxygenase, AtMIOX, EC 1.13.1.11, EC 1.99.2.6, GsMIOX1a, Inositol oxygenase, inositol oxygenase 1, InOx, Kidney-specific protein 32, meso-Inositol oxygenase, MIOX, MIOX1, MIOX2, MIOX4, MIOX5, mMIOX, MOO, Myo-inositol oxygenase, OsMIOX, Oxygenase, inositol, ppMIOX, Renal-specific oxidoreductase, renal-specific oxidoreductase/myo-inositol oxygenase, RSOR/MIOX

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.99 Miscellaneous

                1.13.99.1 inositol oxygenase

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Results	in table
20	Activating Compound
3894	AA Sequence
4	Application
1	CAS Registry Number
42	Cloned(Commentary)
1	Cofactor
3	Crystallization (Commentary)
45	Disease/ Diagnostics
35	Expression
41	General Information
5	General Stability
76	Inhibitors
2	Ki Value [mM]
21	KM Value [mM]
11	Localization
24	Metals/Ions
19	Molecular Weight [Da]
43	Natural Substrates/ Products (Substrates)
86	Organism
3	Oxidation Stability
5	Pathway
4	PDB ID
18	pH Optimum
5	pH Range
3	pH Stability
1	pI Value
1	Posttranslational Modification
18	Protein Variants
19	Purification (Commentary)
3	Reaction
6	Reaction Type
74	Reference
116	Source Tissue
14	Specific Activity [micromol/min/mg]
4	Storage Stability
69	Substrates and Products (Substrate)
23	Subunits
180	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
4	Temperature Range [°C]
4	Temperature Stability [°C]
8	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 1.13.99.1 - inositol oxygenase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

1,10-phenanthroline

Sporopachydermia lactativora

Q70GL3

-

660561

2,4,6-Tripyridyl-(2)-1,3,5-triazine

Rattus norvegicus

-

-

6870

2-Thenoyltrifluoroacetone

Rattus norvegicus

-

slight

6866

3-Aminopicolinate

Sus scrofa

-

-

6868

5,5'-dithiobis(2-nitrobenzoate)

Sus scrofa

-

-

6874

6-(4-hydroxy-3,5-dimethoxyphenyl)-4,8-dihydronaphthalene-1,3,8-triol

Homo sapiens

-

docking energy level (Kcal/mol): -6.9602

727646

8-hydroxyquinoline

2 entries

ADP

2 entries

Ag+

Rattus norvegicus

-

-

6866

alpha,alpha'-bipyridine

Sus scrofa

-

-

6874

alpha-ketoglutarate

Sus scrofa

-

-

6874

AMP

Rattus norvegicus

-

-

6866

arsenite

Rattus norvegicus

-

-

6866

ascochitine

Homo sapiens

-

docking energy level (Kcal/mol): -9.5382

727646

ATP

2 entries

azide

2 entries

Barbital

Sus scrofa

-

-

6874

CTP

Rattus norvegicus

-

-

6866

Cu2+

2 entries

cyanide

2 entries

D-glucarate

2 entries

D-Glucodialdehyde

Sus scrofa

-

weak

6875

diethyldithiocarbamate

Sus scrofa

-

-

6874

EDTA

Sus scrofa

-

-

6874

Epi-Inositol

Sus scrofa

-

-

6875

FAD

Rattus norvegicus

-

-

6866

Fe3+

Sus scrofa

-

-

6874

ferricyanide

Sus scrofa

-

-

6874

ferrocyanide

Sus scrofa

-

-

6874

Furoylthiofluoroacetone

Rattus norvegicus

-

slight

6866

glyoxylate

Sus scrofa

-

-

6874

GTP

2 entries

H2O2

Sus scrofa

-

-

6874, 6875

heritonin

Homo sapiens

-

docking energy level (Kcal/mol): -10.4072

727646

Hg2+

2 entries

hydroxylamine

Rattus norvegicus

-

-

6866

iodoacetate

2 entries

menadione

Rattus norvegicus

-

-

6866

myo-Inosose-1

Sus scrofa

-

-

6875

N-ethylmaleimide

Sus scrofa

-

slight

6874

NAD+

Rattus norvegicus

-

-

6866

NADP+

Rattus norvegicus

-

-

6866

o-phenanthroline

3 entries

oxalacetate

Sus scrofa

-

-

6874

oxalate

Sus scrofa

-

-

6874

p-chloromercuribenzoate

3 entries

Phenobarbital

Sus scrofa

-

-

6874

Phenylmercuric nitrate

Rattus norvegicus

-

-

6866

pyruvate

Sus scrofa

-

-

6874

Quinacrine hydrochloride

Rattus norvegicus

-

slight

6866

riboflavin phosphate

Rattus norvegicus

-

-

6866

Sodium borohydride

Sus scrofa

-

-

6874

stigmasterol

Homo sapiens

-

docking energy level (Kcal/mol): -14.589

727646

taraxasterol

Homo sapiens

-

docking energy level (Kcal/mol): -14.8894

727646

tetrahydrofolic acid

Rattus norvegicus

-

-

6866

tretinoin

Homo sapiens

-

docking energy level (Kcal/mol): -12.1034

727646

UDP

Sus scrofa

-

-

6874

Uridine diphosphoglucose

Rattus norvegicus

-

-

6866

UTP

2 entries

xanthurenic acid

Sus scrofa

-

-

6874

8-hydroxyquinoline

Rattus norvegicus

-

-

6866

8-hydroxyquinoline

Sus scrofa

-

-

6874

ADP

Rattus norvegicus

-

slight

6866

ADP

Sus scrofa

-

-

6874

ATP

Rattus norvegicus

-

-

6866

ATP

Sus scrofa

-

-

6874

azide

Rattus norvegicus

-

-

6866

azide

Sus scrofa

-

-

6874

Cu2+

Rattus norvegicus

-

-

6866

Cu2+

Sus scrofa

-

-

6874

cyanide

Rattus norvegicus

-

-

6866

cyanide

Sus scrofa

-

-

6874

D-glucarate

Homo sapiens

Q9UGB7

a MIOX inhibitor

745184

D-glucarate

Mus musculus

Q9QXN5

a MIOX inhibitor, D-glucarate normalizes reduced autophagy and mitophagy in tubules of STZ-induced diabetic mice

745184

GTP

Rattus norvegicus

-

-

6866

GTP

Sus scrofa

-

-

6874

Hg2+

Rattus norvegicus

-

-

6866

Hg2+

Sus scrofa

-

-

6874

iodoacetate

Rattus norvegicus

-

-

6866

iodoacetate

Sus scrofa

-

-

6874

o-phenanthroline

Rattus norvegicus

-

slight

6866

o-phenanthroline

Rattus norvegicus

-

-

6870

o-phenanthroline

Sus scrofa

-

-

6874

p-chloromercuribenzoate

Rattus norvegicus

-

-

6866

p-chloromercuribenzoate

Sporopachydermia lactativora

Q70GL3

-

660561

p-chloromercuribenzoate

Sus scrofa

-

-

6874

UTP

Rattus norvegicus

-

-

6866

UTP

Sus scrofa

-

-

6874