1.14.11.1: gamma-butyrobetaine dioxygenase
This is an abbreviated version!
For detailed information about gamma-butyrobetaine dioxygenase, go to the full flat file.
Word Map on EC 1.14.11.1
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1.14.11.1
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cardioprotective
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carnitine-dependent
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3-2,2,2-trimethylhydrazinium
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mildronate
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trimethyllysine
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mid1
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alpha4
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medicine
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d-carnitine
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dihydrate
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drug development
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molecular biology
- 1.14.11.1
-
cardioprotective
-
carnitine-dependent
-
3-2,2,2-trimethylhydrazinium
- mildronate
- trimethyllysine
- mid1
-
alpha4
- medicine
- d-carnitine
- dihydrate
- drug development
- molecular biology
Reaction
Synonyms
4-trimethylaminobutyric acid dioxygenase, alpha-butyrobetaine hydroxylase, BBD, BBH, BBOX, BBOX1, Bu hydroxylase, butyrobetaine hydroxylase, gamma butyrobetaine hydroxylase, gamma-BBD, gamma-BBH, gamma-buryrobetaine dioxygenase, gamma-butyrobetaine dioxygenase, gamma-butyrobetaine hydroxylase, gamma-butyrobetaine hydroxylase 1, GBB hydroxylase, GBBH, hBBOX, oxygenase, gamma-butyrobetaine di-, psBBOX
ECTree
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Subunits
Subunits on EC 1.14.11.1 - gamma-butyrobetaine dioxygenase
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dimer
homodimer
additional information
dimer
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SDS-PAGE, same value for all three isozymes, dimeric combinations of two subunits
dimer
the GBBH monomer consists of a catalytic double-stranded beta-helix domain, and a smaller N-terminal domain, the N-terminal domain of GBBH has a similar fold to the DUF971 superfamily. GBBH is dimeric in its biological state. the dimerization interface of GBBH is very different from that of related enzymes, three-dimensional structure, overview
dimer
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1 * 39000 + 1 * 37000, SDS-PAGE, amino acid analysis, N-terminal amino acid sequence
dimer
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2 * 43000, amino acid analysis, a chain of 383 amino acids and a truncated chain of 382 amino acids
dimer
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1 * 39000 + 1 * 37000, SDS-PAGE, amino acid analysis, N-terminal amino acid sequence
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dimer
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2 * 43000, amino acid analysis, a chain of 383 amino acids and a truncated chain of 382 amino acids
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homodimer
BBOX is a homodimer comprising of catalytic domain where Fe(II) and substrates bind and zinc binding domain