1.14.11.27: [histone H3]-dimethyl-L-lysine36 demethylase

This is an abbreviated version!
For detailed information about [histone H3]-dimethyl-L-lysine36 demethylase, go to the full flat file.

Word Map on EC 1.14.11.27

1.14.11.27

demethylases

chromatin

demethylation

h3k9me3

trimethylation

jumonji

tumorigenesis

methyltransferases

lysine-specific

heterochromatin

tri-methylated

tudor

chromatin-modifying

jmjd1a

jmjc-domain-containing

setdb1

Reaction

Show molfile — a [histone H3]-N6,N6-dimethyl-L-lysine36

+ 2 2-oxoglutarate + 2 O2 =

+ 2 succinate + 2 formaldehyde + 2 CO2

Synonyms

dKDM2, dKDM4A, dRAF, GASC1, H3-K36 demethylase, H3-K36-specific demethylase, H3K36 demethylase, H3K36me2 demethylase, H3K36me2 histone demethylase, H3K36me2-specific demethylase, histone H3 lysine 36 demethylase, histone H3 lysine 36 dimethyl�specific demethylase, histone-lysine(H3-K36) demethylase, Jhd1, JHDM1A, Jhdm1b/Kdm2b, JmjC domain histone demethylase, JmjC domain-containing histone demethylase 1, JmjC domain-containing histone demethylase 1A, JmjC domain-containing histone demethylation protein 1, JMJD2, JMJD2A, JMJD5, JMJD7, Kdm2a, KDM2B, KDM2b/JHDM1b, KDM4, KDM4A, KDM4B, Kdm4c, KDM4D, KDM8, lysine demethylase, More, Ndy1, PfJmjC1, PfSET1, scJHDM1, SET1, [histone-H3]-lysine-36 demethylase 1

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase

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All data fields related to EC 1.14.11.27
Results	in table
4	Activating Compound
1348	AA Sequence
4	Application
1	CAS Registry Number
17	Cloned(Commentary)
1	Crystallization (Commentary)
1894	Disease/ Diagnostics
2	Expression
45	General Information
8	Localization
4	Metals/Ions
2	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
94	Organism
113	PDB ID
1	Posttranslational Modification
24	Protein Variants
4	Purification (Commentary)
3	Reaction
30	Reference
28	Source Tissue
52	Substrates and Products (Substrate)
4	Subunits
77	Synonyms
1	Systematic Name

Subunits

Subunits on EC 1.14.11.27 - [histone H3]-dimethyl-L-lysine36 demethylase

for references in articles please use BRENDA:EC1.14.11.27

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oligomer

Saccharomyces cerevisiae

P40034

x * 56500, calculated

688966

additional information

15 entries