1.14.11.29: hypoxia-inducible factor-proline dioxygenase

This is an abbreviated version!
For detailed information about hypoxia-inducible factor-proline dioxygenase, go to the full flat file.

Word Map on EC 1.14.11.29

Reaction

hypoxia-inducible factor-L-proline
+
2-oxoglutarate
+
O2
=
hypoxia-inducible factor-trans-4-hydroxy-L-proline
+
succinate
+
CO2

Synonyms

EGLN, EGLN1, Egln2, EGLN3, factor inhibiting HIF, FIH, HIF hydroxylase, HIF prolyl, HIF prolyl 4-hydroxylase, HIF prolyl hydroxylase, HIF-1alpha PHD3, HIF-1alpha prolyl hydroxylase 3, HIF-alpha prolyl-hydroxylase, HIF-P4H-1, HIF-P4H-2, HIF-P4H-3, HIF-PH, Hif-prolyl hydroxylase, HIF-prolyl hydroxylase domain 2, HIF-prolyl hydroxylase-2, HPH-1, HPH-2, HPH-3, hydroxylase domain enzyme, hypoxia-inducible factor prolyl hydroxylase 2, hypoxia-inducible factor prolyl hydroxylase domain 2, PHD, PHD1, PHD2, PHD3, proline hydroxylase domain 2, prolyl 4-hydroxylase, prolyl hydroxylase, prolyl hydroxylase domain, prolyl hydroxylase domain protein, prolyl hydroxylase domain protein 2, prolyl hydroxylase-2, prolyl-4-hydroxylase 2, prolyl-4-hydroxylase domain 2

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.29 hypoxia-inducible factor-proline dioxygenase

Sequence

Sequence on EC 1.14.11.29 - hypoxia-inducible factor-proline dioxygenase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
Sequence
EGL9_CAEEL
723
0
79743
Swiss-Prot
EGLN1_HUMAN
426
0
46021
Swiss-Prot
EGLN1_MOUSE
400
0
43111
Swiss-Prot
EGLN1_RAT
338
0
36093
Swiss-Prot
EGLN2_HUMAN
407
0
43650
Swiss-Prot
EGLN2_MOUSE
419
0
45109
Swiss-Prot
EGLN2_RAT
415
0
44681
Swiss-Prot
EGLN3_HUMAN
239
0
27261
Swiss-Prot
EGLN3_MOUSE
239
0
27302
Swiss-Prot
EGLN3_RAT
239
0
27242
Swiss-Prot
P4HTM_HUMAN
502
1
56661
Swiss-Prot
P4HTM_MOUSE
503
1
57049
Swiss-Prot
A0A061IG52_CRIGR
140
0
15833
TrEMBL
A0A061IG52_CRIGR
140
0
15833
TrEMBL
A0A061HTK4_CRIGR
390
0
41860
TrEMBL
A0A380T8G5_9PSED
210
0
23842
TrEMBL
A0A061IBH8_CRIGR
126
0
14425
TrEMBL
A0A140EDB6_MEGAM
238
0
26846
TrEMBL
A0A140EDB6_MEGAM
238
0
26846
TrEMBL
A0A0K0M9M3_MYTGA
81
0
9440
TrEMBL