1.14.11.3: pyrimidine-deoxynucleoside 2'-dioxygenase

This is an abbreviated version, for detailed information about pyrimidine-deoxynucleoside 2'-dioxygenase, go to the full flat file.

Reaction

2'-deoxyuridine
+
2-oxoglutarate
+
O2
=
uridine
+
succinate
+
CO2

Synonyms

deoxyuridine 2'-dioxygenase, deoxyuridine 2'-hydroxylase, JBP1, JBP2, pyrimidine deoxyribonucleoside 2'-hydroxylase, thymidine 2'-dioxygenase, thymidine 2'-hydroxylase, thymidine 2-oxoglutarate dioxygenase, thymidine dioxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.3 pyrimidine-deoxynucleoside 2'-dioxygenase

Reference

Reference on EC 1.14.11.3 - pyrimidine-deoxynucleoside 2'-dioxygenase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Warn-Cramer, B.J.; Macrander, L.A.; Abbott, M.T.
Markedly different ascorbate dependencies of the sequential alpha-ketoglutarate dioxygenase reactions catalyzed by an essentially homogeneous thymine 7-hydroxylase from Rhodotorula glutinis
J. Biol. Chem.
258
10551-10557
1983
Rhodotorula glutinis
Manually annotated by BRENDA team
Wondrack, L.M.; Hsu, C.A.; Abbott, M.T.
Thymine 7-hydroxylase and pyrimidine desoxyribonucleoside 2'-hydroxylase activities in Rhodotorula glutinis
J. Biol. Chem.
253
6511-6515
1978
Rhodotorula glutinis
Manually annotated by BRENDA team
Stubbe, J.
Identification of two alpha-ketoglutarate-dependent dioxygenases in extracts of Rhodotorula glutinis catalyzing deoxyuridine hydroxylation
J. Biol. Chem.
260
9972-9975
1985
Rhodotorula glutinis
Manually annotated by BRENDA team
Holme, E.
Purification of thymidine 2'-hydroxylase from Neurospora crassa
Acta Chem. Scand.
37
743-745
1983
Neurospora crassa, Neurospora crassa STA 4
Manually annotated by BRENDA team
Bankel, L.; Lindstedt, G.; Lindstedt, S.
Thymidine 2-hydroxylation in Neurospora crassa
J. Biol. Chem.
247
6128-6134
1972
Neurospora crassa, Neurospora crassa STA 4
Manually annotated by BRENDA team
Liu, C.K.; Shaffer, P.M.; Slaughter, R.S.; McCroskey, R.P.; Abbott, M.T.
Stoichiometry of the pyrimidine deoxyribonucleoside 2-hydroxylase reaction and of the conversions of 5-hydroxymethyluracil to 5-formyluracil and of the latter to uracil-5-carboxylic acid
Biochemistry
11
2172-2176
1972
Neurospora crassa 1A, Neurospora crassa
Manually annotated by BRENDA team
Shaffer, P.M.; McCroskey, R.P.; Abbott, M.T.
Substrate specificity of the hydroxylase reaction in which thymidine is converted to thymine ribonucleoside
Biochim. Biophys. Acta
258
387-394
1972
Neurospora crassa 1A, Neurospora crassa
Manually annotated by BRENDA team
Shaffer, P.M.; McCroskey, R.P.; Palmatier, R.D.; Midgett, R.J.; Abbott, M.T.
The cell-free conversion of a deoxyribonucleoside to a ribonucleoside without detachment of the deoxyribose
Biochem. Biophys. Res. Commun.
33
806-811
1968
Neurospora crassa 1A, Neurospora crassa
Manually annotated by BRENDA team
Cliffe, L.J.; Hirsch, G.; Wang, J.; Ekanayake, D.; Bullard, W.; Hu, M.; Wang, Y.; Sabatini, R.
JBP1 and JBP2 proteins are Fe2+/2-oxoglutarate-dependent dioxygenases regulating hydroxylation of thymidine residues in trypanosome DNA
J. Biol. Chem.
287
19886-19895
2012
Leishmania major, Leishmania tarentolae, Trypanosoma brucei, Trypanosoma brucei 427, Trypanosoma cruzi
Manually annotated by BRENDA team