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1.14.11.35: 1-deoxypentalenic acid 11beta-hydroxylase

This is an abbreviated version!
For detailed information about 1-deoxypentalenic acid 11beta-hydroxylase, go to the full flat file.

Reaction

1-deoxypentalenate
+
2-oxoglutarate
+
O2
=
1-deoxy-11beta-hydroxypentalenate
+
succinate
+
CO2

Synonyms

pntH, ptlH, sav2991

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.35 1-deoxypentalenic acid 11beta-hydroxylase

Engineering

Engineering on EC 1.14.11.35 - 1-deoxypentalenic acid 11beta-hydroxylase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
R117Q
complete loss of activity
R188Q
280fold decrease in activity