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1.14.11.37: kanamycin B dioxygenase

This is an abbreviated version!
For detailed information about kanamycin B dioxygenase, go to the full flat file.

Reaction

kanamycin B
+
2-oxoglutarate
+
O2
=
2'-dehydrokanamycin A
+
succinate
+
NH3
+
CO2

Synonyms

kanJ

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.37 kanamycin B dioxygenase

Reference

Reference on EC 1.14.11.37 - kanamycin B dioxygenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sucipto, H.; Kudo, F.; Eguchi, T.
The last step of kanamycin biosynthesis: unique deamination reaction catalyzed by the alpha-ketoglutarate-dependent nonheme iron dioxygenase KanJ and the NADPH-dependent reductase KanK
Angew. Chem. Int. Ed. Engl.
51
3428-3431
2012
Streptomyces kanamyceticus
Manually annotated by BRENDA team
Gao, W.; Wu, Z.; Sun, J.; Ni, X.; Xia, H.
Modulation of kanamycin B and kanamycin A biosynthesis in Streptomyces kanamyceticus via metabolic engineering
PLoS ONE
12
e0181971
2017
Streptomyces kanamyceticus (Q6L732), Streptomyces kanamyceticus CG305 (Q6L732)
Manually annotated by BRENDA team