1.14.11.37: kanamycin B dioxygenase This is an abbreviated version! For detailed information about kanamycin B dioxygenase, go to the full flat file .
Reaction
kanamycin B +
2-oxoglutarate +
O2 =
2'-dehydrokanamycin A +
succinate +
NH3 +
CO2
Synonyms kanJ
ECTree
Systematic Name
Systematic Name on EC 1.14.11.37 - kanamycin B dioxygenase
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kanamycin-B,2-oxoglutarate:oxygen oxidoreductase (deaminating, 2'-hydroxylating)
Requires Fe2+ and ascorbate. Found in the bacterium Streptomyces kanamyceticus where it is involved in the conversion of the aminoglycoside antibiotic kanamycin B to kanamycin A.