1.14.11.52: validamycin A dioxygenase
This is an abbreviated version!
For detailed information about validamycin A dioxygenase, go to the full flat file.
Reaction
Synonyms
VldW
ECTree
1.14.11.52 validamycin A dioxygenaseAdvanced search results
results (
results (Results
in table
34
Substrates Products
Substrates Products on EC 1.14.11.52 - validamycin A dioxygenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
validoxylamine A + 2-oxoglutarate + O2
?
the enzyme is also able to convert validoxylamine A to its hydroxylated derivative, albeit much less efficiently than the conversion of validamycin A to validamycin B
-
-
?
additional information
?
-
no products are observed when validamine, validamine 7-phosphate, or validoxylamine A 7'-phosphate are used as substrate
-
-
?
validamycin A + 2-oxoglutarate + O2
validamycin B + succinate + CO2
-
-
-
?
validamycin A + 2-oxoglutarate + O2
validamycin B + succinate + CO2
validamycin A i.e. (1R,2R,3S,4S,6R)-2,3-dihydroxy-6-(hydroxymethyl)-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]cyclohexyl beta-D-glucopyranoside
validamycin B i.e. (1R,2R,3S,4S,5R,6S)-2,3,5-trihydroxy-6-(hydroxymethyl)-4-8[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]cyclohexyl beta-D-glucopyranoside
-
?
