1.14.11.54: mRNA N1-methyladenine demethylase
This is an abbreviated version!
For detailed information about mRNA N1-methyladenine demethylase, go to the full flat file.
Word Map on EC 1.14.11.54
-
1.14.11.54
-
paraneoplastic
-
pokeweed
-
anti-yo
-
anna-1
-
cd45ra
-
anti-il-6
-
cell-restricted
-
medicine
- 1.14.11.54
-
paraneoplastic
-
pokeweed
-
anti-yo
-
anna-1
-
cd45ra
-
anti-il-6
-
cell-restricted
- medicine
Reaction
Synonyms
ABH3, AlkB, AlkB homolog 3, ALKBH3, alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, PCA-1, prostate cancer antigen-1
ECTree
Advanced search results
Engineering
Engineering on EC 1.14.11.54 - mRNA N1-methyladenine demethylase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
D135I
the mutant shows increased activity with RNA-N6-methyladenine and reduced activity with DNA-N1-methyladenine compared to the wild type enzyme
D135N
the mutant shows increased activity with RNA-N6-methyladenine and reduced activity with DNA-N1-methyladenine compared to the wild type enzyme
E136L
the mutant shows increased activity with RNA-N6-methyladenine and reduced activity with DNA-N1-methyladenine compared to the wild type enzyme
L177A
mutation at the active site, mutant lost its demethylation activity on m1A of tRNA in vitro and in vivo
R122A
mutant is defective in its DNA/RNA binding groove, mutant lost its demethylation activity on m1A of tRNA in vitro and in vivo