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1.14.11.B19: [histone H3]-trimethyl-L-lysine56 demethylase

This is an abbreviated version!
For detailed information about [histone H3]-trimethyl-L-lysine56 demethylase, go to the full flat file.

Reaction

a [histone H3]-N6,N6,N6-trimethyl-L-lysine56
+
2-oxoglutarate
+
O2
=
a [histone H3]-N6,N6-dimethyl-L-lysine56
+
succinate
+
formaldehyde
+
CO2

Synonyms

JMJD2D, KDM4DL, KDM4E, lysine-specific demethylase 4E

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.B19 [histone H3]-trimethyl-L-lysine56 demethylase

Localization

Localization on EC 1.14.11.B19 - [histone H3]-trimethyl-L-lysine56 demethylase

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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
KDM4A predominantly localizes to heterochromatin and regulates heterochromatin position-effect variegation, organization of repetitive DNAs, and DNA repair
Manually annotated by BRENDA team