1.14.11.B19: [histone H3]-trimethyl-L-lysine56 demethylase
This is an abbreviated version!
For detailed information about [histone H3]-trimethyl-L-lysine56 demethylase, go to the full flat file.
Reaction
Synonyms
JMJD2D, KDM4DL, KDM4E, lysine-specific demethylase 4E
ECTree
1.14.11.B19 [histone H3]-trimethyl-L-lysine56 demethylaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 1.14.11.B19 - [histone H3]-trimethyl-L-lysine56 demethylase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
[histone H3]-N6,N6,N6-trimethyl-L-lysine56 + 2 2-oxoglutarate + 2 O2
[histone H3]-N6-methyl-L-lysine56 + 2 succinate + 2 formaldehyde + 2 CO2
[histone H3]-N6,N6,N6-trimethyl-L-lysine56 + 2-oxoglutarate + O2
[histone H3]-N6,N6-dimethyl-L-lysine56 + succinate + formaldehyde + CO2
[histone H3]-N6,N6-dimethyl-L-lysine56 + 2-oxoglutarate + O2
[histone H3]-N6-methyl-L-lysine56 + succinate + formaldehyde + CO2
[histone H3]-N6,N6,N6-trimethyl-L-lysine56 + 2 2-oxoglutarate + 2 O2
[histone H3]-N6-methyl-L-lysine56 + 2 succinate + 2 formaldehyde + 2 CO2
-
-
-
?
[histone H3]-N6,N6,N6-trimethyl-L-lysine56 + 2 2-oxoglutarate + 2 O2
[histone H3]-N6-methyl-L-lysine56 + 2 succinate + 2 formaldehyde + 2 CO2
-
-
-
?
[histone H3]-N6,N6,N6-trimethyl-L-lysine56 + 2 2-oxoglutarate + 2 O2
[histone H3]-N6-methyl-L-lysine56 + 2 succinate + 2 formaldehyde + 2 CO2
-
-
-
?
[histone H3]-N6,N6,N6-trimethyl-L-lysine56 + 2-oxoglutarate + O2
[histone H3]-N6,N6-dimethyl-L-lysine56 + succinate + formaldehyde + CO2
-
-
-
?
[histone H3]-N6,N6,N6-trimethyl-L-lysine56 + 2-oxoglutarate + O2
[histone H3]-N6,N6-dimethyl-L-lysine56 + succinate + formaldehyde + CO2
-
-
-
?
[histone H3]-N6,N6,N6-trimethyl-L-lysine56 + 2-oxoglutarate + O2
[histone H3]-N6,N6-dimethyl-L-lysine56 + succinate + formaldehyde + CO2
-
-
-
?
[histone H3]-N6,N6-dimethyl-L-lysine56 + 2-oxoglutarate + O2
[histone H3]-N6-methyl-L-lysine56 + succinate + formaldehyde + CO2
-
-
-
?
[histone H3]-N6,N6-dimethyl-L-lysine56 + 2-oxoglutarate + O2
[histone H3]-N6-methyl-L-lysine56 + succinate + formaldehyde + CO2
-
-
-
?
[histone H3]-N6,N6-dimethyl-L-lysine56 + 2-oxoglutarate + O2
[histone H3]-N6-methyl-L-lysine56 + succinate + formaldehyde + CO2
-
-
-
?
additional information
?
-
trimethylation of H3K56 is removed by members of the JMJD2 family of demethylases that also target H3K9me3, reaction of EC 1.14.11.65
-
-
?
additional information
?
-
trimethylation of H3K56 is removed by members of the JMJD2 family of demethylases that also target H3K9me3, reaction of EC 1.14.11.65
-
-
?
