Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.12.12: naphthalene 1,2-dioxygenase

This is an abbreviated version!
For detailed information about naphthalene 1,2-dioxygenase, go to the full flat file.

Word Map on EC 1.14.12.12

Reaction

Naphthalene
+
NADH
+
H+
+
O2
=
(1R,2S)-1,2-dihydronaphthalene-1,2-diol
+
NAD+

Synonyms

NAG, NAHA, nahAc, naphthalene 1,2-dioxygenase, naphthalene dioxygenase, naphthalene oxygenase, NDO, oxygenase, naphthalene di-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.12 naphthalene 1,2-dioxygenase

General Stability

General Stability on EC 1.14.12.12 - naphthalene 1,2-dioxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
10% ethanol and 10% glycerol are required for stability
-
dialysis inactivates rapidly, NaBH4 and dithioerythritol restore activity
-
dilution inactivates rapidly, NaBH4 and dithioerythritol restore activity
-
DTT stabilizes
-
purification of reductase leads to significant loss of flavin cofactor
-