1.14.12.16: 2-Hydroxyquinoline 5,6-dioxygenase

This is an abbreviated version!
For detailed information about 2-Hydroxyquinoline 5,6-dioxygenase, go to the full flat file.

Reaction

quinolin-2-ol
+
NADH
+
H+
+
O2
=
2,5,6-trihydroxy-5,6-dihydroquinoline
+
NAD+

Synonyms

2-Hydroxyquinoline 5,6-dioxygenase, 2-oxo-1,2-dihydroquinoline 5,6-dioxygenase, Oxygenase, 2(1H)-quinolinone 5,6-di-, Quinolin-2(1H)-one 5,6-dioxygenase, Quinolin-2-ol 5,6-dioxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.16 2-Hydroxyquinoline 5,6-dioxygenase

Metals Ions

Metals Ions on EC 1.14.12.16 - 2-Hydroxyquinoline 5,6-dioxygenase

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Fe2+
-
enhances activity 1.5fold