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1.14.12.19: 3-phenylpropanoate dioxygenase

This is an abbreviated version!
For detailed information about 3-phenylpropanoate dioxygenase, go to the full flat file.

Reaction

(2E)-3-phenylprop-2-enoate
+
NADH
+
H+
+
O2
=
(2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate
+
NAD+

Synonyms

3-phenylpropionate dioxygenase, Hca dioxygenase, HcA1A2CD, HcaA1A2CD

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.19 3-phenylpropanoate dioxygenase

Natural Substrates Products

Natural Substrates Products on EC 1.14.12.19 - 3-phenylpropanoate dioxygenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
3-phenylpropionate + NADH + H+ + O2
3-(2,3-dihydroxyphenyl)propionate + NAD+
show the reaction diagram
3-phenylpropionate + NADH + H+ + O2
3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+
show the reaction diagram
-
enables utilization of 3-phenylpropionate as carbon source
-
-
?
3-phenylpropionate + NADH + H+ + O2
3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dien-1-yl]propanoic acid + NAD+
show the reaction diagram