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1.14.12.24: 2,4-dinitrotoluene dioxygenase

This is an abbreviated version!
For detailed information about 2,4-dinitrotoluene dioxygenase, go to the full flat file.

Word Map on EC 1.14.12.24

Reaction

2,4-dinitrotoluene
+
NADH
 +
O2
=
4-methyl-5-nitrocatechol
 +
nitrite
 +
NAD+

Synonyms

2,4-dinitrotoluene dioxygenase, 2,4-DNT dioxygenase, 2,4-DNTDO, DDO, DNT dioxygenase, dntA, DntAc, DNTDO

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.24 2,4-dinitrotoluene dioxygenase

Activating Compound

Activating Compound on EC 1.14.12.24 - 2,4-dinitrotoluene dioxygenase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
-
required for maximal activity, 292.3% activity at 1% (v/v)
ATP
-
124% activity at 0.1 mM
FMN
-
230.7% activity at 0.1 mM
GTP
-
116% activity at 0.1 mM
lipase
-
176% activity at 1 mg per g wet weight of cells
-
NADP+
-
2fold enhancement of activity in the presence of NADP+
phosphatidylcholine
-
125% activity at 0.05 mg
phosphatidylethanolamine
-
144% activity at 0.1 mg per g wet weight of cells
Phospholipase A
-
125% activity at 0.01 mg
-
Vitreoscilla hemoglobin
-