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1.14.12.25: p-cumate 2,3-dioxygenase

This is an abbreviated version!
For detailed information about p-cumate 2,3-dioxygenase, go to the full flat file.

Reaction

p-cumate
+
NADH
+
H+
+
O2
=
(2R,3S)-2,3-dihydroxy-2,3-dihydro-p-cumate
+
NAD+

Synonyms

CmtAa, CmtAb, CmtAc, CmtAd, p-cumate dioxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.25 p-cumate 2,3-dioxygenase

General Information

General Information on EC 1.14.12.25 - p-cumate 2,3-dioxygenase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
-
a mutant of Pseudomonas putida, which is unable to grow with p-cumate, accumulates 2,3-dihydroxy-4-isoproplycyclohexa-4,6-dienoate. Both hydroxyl atoms of the dihydrodiol are derived from the same molecule of 02