Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.12.3: benzene 1,2-dioxygenase

This is an abbreviated version!
For detailed information about benzene 1,2-dioxygenase, go to the full flat file.

Word Map on EC 1.14.12.3

Reaction

Benzene
+
NADH
+
H+
+
O2
=
cis-cyclohexa-3,5-diene-1,2-diol
+
NAD+

Synonyms

BDO, BED, benzene dioxygenase, benzene hydroxylase, More, oxygenase, benzene 1,2-di-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.3 benzene 1,2-dioxygenase

Substrates Products

Substrates Products on EC 1.14.12.3 - benzene 1,2-dioxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1-methylcyclohexene + O2 + NADH
?
show the reaction diagram
2 cyclohexene + 2 O2 + 2 NADH + 2 H+
2-cyclohexen-1-ol + cis-1,2-cyclohexanediol + 2 NAD+ + H2O
show the reaction diagram
-
-
failure of transformed bacteria to grow on cyclohexene is attributed to the toxicity of metabolic intermediates accumulating from the 2-cyclohexen-1-ol metabolism, cyclohexene metabolism pathways, overview
-
?
3-methylcyclohexene + O2 + NADH
?
show the reaction diagram
benzene + NADH + H+ + O2
cis-cyclohexa-3,5-diene-1,2-diol + NAD+
show the reaction diagram
benzene + NADH + O2
(1R,2S)-cis-cyclohexa-3,5-diene-1,2-diol + NAD+
show the reaction diagram
benzene + NADH + O2
?
show the reaction diagram
benzene + NADH + O2
cis-cyclohexa-3,5-diene-1,2-diol + NAD+
show the reaction diagram
benzene + NADPH + O2
cis-cyclohexa-3,5-diene-1,2-diol + NADP+
show the reaction diagram
-
activity with NADPH is 10% of the activity with NADH
-
-
?
benzene + O2 + NADH
cis-cyclohexa-3,5-diene-1,2-diol + NAD+
show the reaction diagram
ethylbenzene + NADH + O2
cis-2,3-dihydroxy-1-ethyl-cyclohexa-4,6-diene + 1-phenethyl alcohol + NAD+
show the reaction diagram
-
-
-
-
?
ethylbenzene + [reduced NADPH-hemoprotein reductase] + O2
cis-2,3-dihydroxy-1-ethyl-cyclohexa-4,6-diene + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
-
?
toluene + NADH + O2
cis-2,3-dihydroxy-1-methyl-cyclohexa-4,6-diene + NAD+
show the reaction diagram
-
-
-
-
?
toluene + O2 + NADH
?
show the reaction diagram
-
-
-
-
?
trifluoromethylbenzene + NADH + O2
?
show the reaction diagram