1.14.12.9: 4-chlorophenylacetate 3,4-dioxygenase

This is an abbreviated version!
For detailed information about 4-chlorophenylacetate 3,4-dioxygenase, go to the full flat file.

Reaction

4-chlorophenylacetate
+
NADH
+
H+
+
O2
=
3,4-Dihydroxyphenylacetate
+
chloride
+
NAD+

Synonyms

EC 1.13.99.4, oxygenase, 4-chlorophenylacetate 3,4-di-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.9 4-chlorophenylacetate 3,4-dioxygenase

Substrates Products

Substrates Products on EC 1.14.12.9 - 4-chlorophenylacetate 3,4-dioxygenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3-chlorophenylacetate + NADH + O2 + H2O
3,4-dihydroxyphenylacetate + Cl- + NAD+
show the reaction diagram
4-bromophenylacetate + NADH + O2 + H2O
3,4-dihydroxyphenylacetate + Br- + NAD+
show the reaction diagram
4-chlorophenylacetate + ferrocytochrome c + H+ + O2
3,4-dihydroxyphenylacetate + chloride + ferricytochrome c
show the reaction diagram
4-chlorophenylacetate + NADH + O2 + H2O
3,4-dihydroxyphenylacetate + Cl- + NAD(P)+
show the reaction diagram
4-chlorophenylacetate + reduced 2,6-dichlorophenolindophenol + O2
3,4-dihydroxyphenylacetate + chloride + oxidized 2,6-dichlorophenolindophenol
show the reaction diagram
4-fluorophenylacetate + NADH + O2 + H2O
3,4-dihydroxyphenylacetate + F- + NAD+
show the reaction diagram
4-hydroxyphenylacetate + NADH + O2 + H2O
3,4-dihydroxyphenylacetate + OH- + NAD+
show the reaction diagram
-
4% of the activity of 4-chlorophenylacetate
-
-
?
phenylacetate + NADH + O2 + H2O
?
show the reaction diagram
-
6% of the activity of 4-chlorophenylacetate
-
-
?
additional information
?
-