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1.14.13.10: 2,6-dihydroxypyridine 3-monooxygenase

This is an abbreviated version!
For detailed information about 2,6-dihydroxypyridine 3-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.10

Reaction

2,6-Dihydroxypyridine
+
NADH
 +
H+
 +
O2
=
2,3,6-Trihydroxypyridine
 +
NAD+
 +
H2O

Synonyms

2,6-dihydroxypyridine hydroxylase, 2,6-dihydroxypyridine oxidase, 2,6-dihydroxypyridine-3-hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.10 2,6-dihydroxypyridine 3-monooxygenase

Inhibitors

Inhibitors on EC 1.14.13.10 - 2,6-dihydroxypyridine 3-monooxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,3-dihydroxypyridine
2,6-dihydroxynicotinamide
-
55% inhibition at 0.1 mM, reversible inhibitor
2,6-dimethoxypyridine
2-Hydroxypyridine
-
48% inhibition at 0.1 mM, reversible inhibitor
Cu2+
-
50% inhibition at 0.017 mM
Hg2+
-
50% inhibition at 0.005 mM
NaN3
-
50% inhibition at 2 mM
p-chloromercuribenzoate
-
50% inhibition at 0.01 mM
resorcine
-
51% inhibition at 0.1 mM, reversible inhibitor
Zn2+
-
50% inhibition at 0.7 mM