1.14.13.101: senecionine N-oxygenase
This is an abbreviated version!
For detailed information about senecionine N-oxygenase, go to the full flat file.
Reaction
Synonyms
flavin-dependent monooxygenase, fmoa, GgPNO, oxygenase, senecionine N-, PA N-oxygenase, PNO, pyrrolizidine alkaloid N-oxygenase, senecionine monooxygenase (N-oxide-forming), senecionine N-oxygenase, SNO, TjSNO, ZvFMOa, ZvPNO
ECTree
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Reference on EC 1.14.13.101 - senecionine N-oxygenase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lindigkeit, R.; Biller, A.; Buch, M.; Schiebel, H.M.; Boppre, M.; Hartmann, T.
The two faces of pyrrolizidine alkaloids: the role of the tertiary amine and its N-oxide in chemical defense of insects with aquired alkaloids
Eur. J. Biochem.
245
626-636
1997
Arctia caja, Tyria jacobaeae, no activity in Spodoptera littoralis, Creatonotos transiens, Callimorpha dominula, Arctia intercalaris, Amerila phaedra, Idea leuconoe, Zonocerus variegatus
Naumann, C.; Hartmann, T.; Ober, D.
Evolutionary recruitment of a flavin-dependent monooxygenase for the detoxification of host plant-defended arctiid moth Tyria jacobaeae
Proc. natl. Acad. Sci. USA
99
6085-6090
2002
Tyria jacobaeae (Q8MP06), Tyria jacobaeae
Chang, A.; Hartmann, T.
Solubilization and characterization of a senecionine N-oxygenase from Crotalaria scassellatii seedlings
Phytochemistry
49
1859-1866
1998
Crotalaria scassellatii
-
Sehlmeyer, S.; Wang, L.; Langel, D.; Heckel, D.G.; Mohagheghi, H.; Petschenka, G.; Ober, D.
Flavin-dependent monooxygenases as a detoxification mechanism in insects: new insights from the arctiids (lepidoptera)
PLoS ONE
5
e10435
2010
Apantesis nevadensis geneura (D6CHF2), Apantesis nevadensis geneura, Tyria jacobaeae (Q8MP06), Tyria jacobaeae
Wang, L.; Beuerle, T.; Timbilla, J.; Ober, D.
Independent recruitment of a flavin-dependent monooxygenase for safe accumulation of sequestered pyrrolizidine alkaloids in grasshoppers and moths
PLoS ONE
7
e31796
2012
Zonocerus variegatus
Kubitza, C.; Faust, A.; Gutt, M.; Gaeth, L.; Ober, D.; Scheidig, A.J.
Crystal structure of pyrrolizidine alkaloid N-oxygenase from the grasshopper Zonocerus variegatus
Acta Crystallogr. Sect. D
74
422-432
2018
Zonocerus variegatus (L0N8F3), Zonocerus variegatus (L0N8S9), Zonocerus variegatus
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