1.14.13.101: senecionine N-oxygenase
This is an abbreviated version!
For detailed information about senecionine N-oxygenase, go to the full flat file.
Reaction
Synonyms
flavin-dependent monooxygenase, fmoa, GgPNO, oxygenase, senecionine N-, PA N-oxygenase, PNO, pyrrolizidine alkaloid N-oxygenase, senecionine monooxygenase (N-oxide-forming), senecionine N-oxygenase, SNO, TjSNO, ZvFMOa, ZvPNO
ECTree
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10
16
18
Subunits
Subunits on EC 1.14.13.101 - senecionine N-oxygenase
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homodimer
additional information
homodimer
HPLC-based size-exclusion chromatography (SEC) with refractive-index (RI) and multi-angle laser light-scattering (MALS) detectors, the isozyme ZvPNO shows a unique dimeric arrangement as well as small conformational changes within the active site. A unique flexible helix close to the active site is observed which is likely to be involved in substrate binding and/or product release. Symmetrical homodimers with twofold symmetry can be observed within the ZvPNO crystal structure with a distinct type of orientation
FMO isozymes' structure analysis and comparisons, overview
additional information
FMO isozymes' structure analysis and comparisons, overview
additional information
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FMO isozymes' structure analysis and comparisons, overview