1.14.13.114: 6-hydroxynicotinate 3-monooxygenase

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For detailed information about 6-hydroxynicotinate 3-monooxygenase, go to the full flat file.

Reaction

Synonyms

6-hydroxynicotinic acid 3-monooxygenase, 6HNA monooxygenase, BB1770, BbNicC, NicC, PpNicC

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.13.114 6-hydroxynicotinate 3-monooxygenase

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Results	in table
509	AA Sequence
2	Application
6	Cloned(Commentary)
11	Cofactor
1	Crystallization (Commentary)
21	General Information
11	Inhibitors
18	kcat/KM [mM/s]
3	Ki Value [mM]
23	KM Value [mM]
2	Localization
2	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
53	Organism
4	Pathway
1	PDB ID
4	pH Optimum
1	pH Range
1	pH Stability
23	Protein Variants
4	Purification (Commentary)
8	Reaction
12	Reference
1	Specific Activity [micromol/min/mg]
25	Substrates and Products (Substrate)
7	Subunits
23	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
2	Temperature Stability [°C]
18	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 1.14.13.114 - 6-hydroxynicotinate 3-monooxygenase

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SYSTEMATIC NAME

IUBMB Comments

6-hydroxynicotinate,NADH:oxygen oxidoreductase (3-hydroxylating, decarboxylating)

A flavoprotein (FAD) [1]. The reaction is involved in the aerobic catabolism of nicotinic acid.