1.14.13.130: pyrrole-2-carboxylate monooxygenase

This is an abbreviated version, for detailed information about pyrrole-2-carboxylate monooxygenase, go to the full flat file.

Reaction

pyrrole-2-carboxylate
+
NADH
+
H+
+
O2
=
5-hydroxypyrrole-2-carboxylate
+
NAD+
+
H2O

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.130 pyrrole-2-carboxylate monooxygenase

Inhibitors

Inhibitors on EC 1.14.13.130 - pyrrole-2-carboxylate monooxygenase

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
5,5'-dithiobis(2-nitrobenzoic acid)
bathophenanthroline disulfonic acid
-
0.005 mM, 5 min incubation, 75% loss of activity
Cu+
-
0.001-0.01 mM, 93% loss of activity
Cu2+
-
1 mM, 5 min incubation, complete inactivation
Hg2+
-
0.01-0.1 mM, 96% loss of activity
Zn2+
-
1 mM, 5 min incubation, complete inactivation
additional information
-
no inhibition by 1 mM EDTA or 1 mM arsenite
-