Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.13.135: 1-hydroxy-2-naphthoate hydroxylase

This is an abbreviated version!
For detailed information about 1-hydroxy-2-naphthoate hydroxylase, go to the full flat file.

Reaction

Show molfile
1-hydroxy-2-naphthoate
+
Show molfile
NAD(P)H
+
Show molfile
H+
+
Show molfile
O2
=
Show molfile
1,2-dihydroxynaphthalene
+
Show molfile
NAD(P)+
+
Show molfile
H2O
+
Show molfile
CO2

Synonyms

1-hydroxy-2-naphthoic acid hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                EC 1.14.13.1351.14.13.135 1-hydroxy-2-naphthoate hydroxylase

Cofactor

Cofactor on EC 1.14.13.135 - 1-hydroxy-2-naphthoate hydroxylase

for references in articles please use BRENDA:EC1.14.13.135

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
FAD
-
holoenzyme contains FAD. Km is 0.0047 mM. Preparation of the apoenzyme by the acid-ammonium sulfate, at 2 M, dialysis method, the apoenzyme is colorless, inactive and loses the characteristic flavin absorption spectra but regains about 90% of maximal activity when reconstituted with FAD
NADH
-
Vmax/Km is similar for NADPH and NADH
NADPH
-
Vmax/Km is similar for NADPH and NADH
additional information
-
FMN is a poor substitute for FAD
-