1.14.13.158: amorpha-4,11-diene 12-monooxygenase

This is an abbreviated version, for detailed information about amorpha-4,11-diene 12-monooxygenase, go to the full flat file.

transferred to EC 1.14.14.114

Synonyms

amorpha-4,11-diene C-12 oxidase, amorpha-4,11-diene monooxygenase, CYP71AV1

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.13.158 amorpha-4,11-diene 12-monooxygenase

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1

Application

6

Cloned(Commentary)

9

Cofactor

2

Engineering

3

Expression

16

General Information

21

Natural Substrates/ Products (Substrates)

5

Organism

2

pH Optimum

9

Reference

11

Source Tissue

23

Substrates and Products (Substrate)

7

Synonyms

Natural Substrates Products

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Natural Substrates Products on EC 1.14.13.158 - amorpha-4,11-diene 12-monooxygenase

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NATURAL SUBSTRATES

NATURAL PRODUCTS

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

amorpha-4,11-diene + 3 O2 + 3 NADPH + 3 H+

artemisinate + 3 NADP+ + 4 H2O

8 entries

amorpha-4,11-diene + O2 + NADPH + H+

artemisinic alcohol + NADP+ + H2O

2 entries

artemisinic alcohol + O2 + NADPH + H+

artemisinic aldehyde + NADP+ + 2 H2O

2 entries

artemisinic aldehyde + O2 + NADPH + H+

artemisinate + NADP+ + H2O

2 entries

amorpha-4,11-diene + 3 O2 + 3 NADPH + 3 H+

artemisinate + 3 NADP+ + 4 H2O

Artemisia absinthium

K7ZPJ9

-

746043

-

-

?

amorpha-4,11-diene + 3 O2 + 3 NADPH + 3 H+

artemisinate + 3 NADP+ + 4 H2O

Artemisia afra

K7ZR99

-

746043

-

-

?

amorpha-4,11-diene + 3 O2 + 3 NADPH + 3 H+

artemisinate + 3 NADP+ + 4 H2O

Artemisia annua

-

-

746043

-

-

?

amorpha-4,11-diene + 3 O2 + 3 NADPH + 3 H+

artemisinate + 3 NADP+ + 4 H2O

Artemisia annua

-

overall reaction via artemsinic alcohol and artemsinic aldehyde, multistep process

745905, 746035

-

-

?

amorpha-4,11-diene + 3 O2 + 3 NADPH + 3 H+

artemisinate + 3 NADP+ + 4 H2O

Artemisia annua

Q1PS23

overall reaction via artemsinic alcohol and artemsinic aldehyde, multistep process

746069

-

-

?

amorpha-4,11-diene + 3 O2 + 3 NADPH + 3 H+

artemisinate + 3 NADP+ + 4 H2O

Artemisia annua

-

overall reaction via artemsinic alcohol and artemsinic aldehyde, multistep process

746309

-

-

?

amorpha-4,11-diene + 3 O2 + 3 NADPH + 3 H+

artemisinate + 3 NADP+ + 4 H2O

Artemisia annua

Q1PS23

overall reaction, multistep process

745821

-

-

?

amorpha-4,11-diene + 3 O2 + 3 NADPH + 3 H+

artemisinate + 3 NADP+ + 4 H2O

Artemisia kurramensis

-

-

746043

-

-

?

amorpha-4,11-diene + O2 + NADPH + H+

artemisinic alcohol + NADP+ + H2O

Artemisia annua

Q1PS23

-

745821

-

-

?

amorpha-4,11-diene + O2 + NADPH + H+

artemisinic alcohol + NADP+ + H2O

Artemisia annua

-

-

745905, 746035, 746309

-

-

?

artemisinic alcohol + O2 + NADPH + H+

artemisinic aldehyde + NADP+ + 2 H2O

Artemisia annua

Q1PS23

-

745821

-

-

?

artemisinic alcohol + O2 + NADPH + H+

artemisinic aldehyde + NADP+ + 2 H2O

Artemisia annua

-

-

745905, 746035, 746309

-

-

?

artemisinic aldehyde + O2 + NADPH + H+

artemisinate + NADP+ + H2O

Artemisia annua

Q1PS23

-

745821

-

-

?

artemisinic aldehyde + O2 + NADPH + H+

artemisinate + NADP+ + H2O

Artemisia annua

-

-

745905, 746035, 746309

-

-

?

Show Natural Substrates (14 entries)