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1.14.13.16: cyclopentanone monooxygenase

This is an abbreviated version!
For detailed information about cyclopentanone monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.16

Reaction

Cyclopentanone
+
NADPH
+
H+
+
O2
=
5-valerolactone
+
NADP+
+
H2O

Synonyms

CPMO, CpnB, cyclopentanone monooxygenase, cyclopentanone oxygenase, More

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.16 cyclopentanone monooxygenase

KM Value

KM Value on EC 1.14.13.16 - cyclopentanone monooxygenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.25
2-Octanone
-
recombinant mutant P253F/G254A/R258M/L443F, pH 7.4, 25°C
0.8
2-phenylcyclohexanone
-
recombinant mutant P253F/G254A/R258M/L443F, pH 7.4, 25°C
0.15 - 1000
Cyclopentanone
0.001
O2
-
-
additional information
additional information
-
steady-state kinetic analysis of the mutant enzyme
-